IDH MUTATION
Clinical trials for IDH MUTATION explained in plain language.
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New drug duo aims to rally immune system against recurrent brain cancer
Disease control Recruiting nowThis study is testing whether combining two drugs—an oral vitamin A derivative (ATRA) and an immunotherapy (retifanlimab)—can help control recurrent brain tumors called IDH-mutant gliomas. The goal is to see if this combination is safe and can shrink tumors or stop their growth. …
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Stephen Bagley, MD, MSCE • Aim: Disease control
Last updated Apr 02, 2026 14:57 UTC
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New drug aims to keep aggressive bile duct cancer at bay after treatment
Disease control Recruiting nowThis study is testing whether a drug called ivosidenib can help prevent cancer from returning in people with a specific type of bile duct cancer who have already had surgery and chemotherapy. The trial will involve about 40 patients who have a particular genetic mutation (IDH1) i…
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Scientists test new Pill's journey to brain tumors
Knowledge-focused Recruiting nowThis early study is testing whether an experimental oral drug called DSP-0390 can reach brain tumors in sufficient amounts and affect tumor cell metabolism. Researchers will give the drug for about two weeks to 20 patients with specific types of brain tumors (grade II/III gliomas…
Matched conditions: IDH MUTATION
Phase: EARLY_PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:43 UTC