IDH MUTATION
Clinical trials for IDH MUTATION explained in plain language.
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New hope for bile duct cancer: targeted pill may prevent return
Disease control Recruiting nowThis study tests whether a daily pill called ivosidenib can help keep bile duct cancer from returning after surgery and chemotherapy. It is for 40 adults with a specific gene mutation (IDH1) whose cancer was completely removed. Participants will take the drug for one year, and re…
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest • Aim: Disease control
Last updated May 26, 2026 06:17 UTC
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New combo aims to wake up immune system against brain cancer
Disease control Recruiting nowThis study tests a combination of two drugs—ATRA and retifanlimab—in people with a type of brain tumor (glioma) that has come back after standard treatment. The goal is to see if this combination can shrink tumors or slow their growth by boosting the body's immune response. About…
Matched conditions: IDH MUTATION
Phase: PHASE2 • Sponsor: Stephen Bagley, MD, MSCE • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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New drug targets brain tumors in short Pre-Surgery study
Knowledge-focused Recruiting nowThis study tests an oral drug called DSP-0390 in 20 people with IDH-mutant gliomas who are scheduled for brain tumor removal. Participants take the drug for about two weeks before surgery, and researchers measure how much drug reaches the tumor and blood. The goal is to see if th…
Matched conditions: IDH MUTATION
Phase: EARLY_PHASE1 • Sponsor: Washington University School of Medicine • Aim: Knowledge-focused
Last updated May 26, 2026 04:37 UTC