ICU ACQUIRED WEAKNESS

This study tests whether giving ICU patients extra protein and activating their muscles early with electrical stimulation can prevent severe muscle loss. About 40 critically ill adults on breathing machines will take part. The goal is to see if this approach helps patients keep m…

This study tests a device that sends mild electrical pulses to the thigh muscles of people in the ICU. The goal is to see if it is safe and practical to use, and whether it can slow down muscle weakening. About 50 critically ill patients will either receive standard care or stand…

This study tests a home-based rehabilitation program using a smartphone app and high-intensity interval training for 120 people who were critically ill with COVID-19. Participants exercise at home while being monitored remotely. The goal is to improve walking distance, fitness, a…

This study looks at whether moving patients who are on breathing machines out of bed and into a chair helps them regain strength and function better than staying in bed. About 150 adults in the ICU will be randomly assigned to either chair sitting or bed sitting. The goal is to s…

This study looks at why many people who survive a serious illness in the ICU develop lasting muscle weakness. Researchers will test the heart and blood flow of 50 former ICU patients during exercise. The goal is to better understand the problem, not to test a new treatment.

This study follows 209 adults who survived a stay in the intensive care unit (ICU) to understand why some never fully regain muscle strength. Researchers will measure physical function and look at muscle cells to find clues. The goal is to identify who is at risk for long-term di…

This study looks at 25 ICU patients who were on breathing machines for at least 2 days. Researchers want to see if a physical test called CPAx, done when leaving the ICU, can predict how well they walk 3 months later. The goal is to help doctors plan better rehab for patients aft…

This study looks at whether giving ICU staff real-time feedback and having a dedicated nurse facilitator can increase the use of a set of proven practices (the ABCDEF bundle) for adults on breathing machines. About 8,100 patients across multiple ICUs will take part. The goal is t…

This study tests whether a smart technology box can help monitor the health of people who have been in the ICU. Researchers want to see if patients can use the device at home for 12 months after leaving the hospital. The goal is to catch complications early and improve recovery. …