HYPERLIPIDEMIA

This study tested two statins, rosuvastatin and pravastatin, to see which is safer and more effective at lowering cholesterol in people with HIV who are on antiretroviral therapy. 86 participants with high cholesterol took one of the two drugs for 45 days. The goal was to manage …

This early-stage study tested a new drug called HRS-1301 in 82 healthy adults to see if it is safe and how the body processes it. The goal is to eventually use this drug to help control high cholesterol. Researchers measured side effects and drug levels in blood and urine.

This study tested a new medicine called SHR-1918, given as multiple shots under the skin, in 44 adults with high cholesterol that was not well controlled by current treatments. The goal was to see if it safely lowers "bad" LDL cholesterol more than a placebo over 24 weeks. Partic…

This study tested whether people with high cholesterol who check their levels at home and report them by phone can lower their LDL more than those getting standard care. 70 adults with LDL over 130 mg/dL took part. The goal was to see if home monitoring improves medication adhere…

This early-stage study tested a single injection of HRS-7249 in 32 to 48 healthy adults with mildly to moderately high cholesterol. The main goal was to check safety and how the drug moves through the body. Participants received either the drug or a placebo, and researchers monit…

This study looked at how a single pill that combines two drugs (pitavastatin for cholesterol and valsartan for blood pressure) works compared to taking the two drugs separately. It involved 52 healthy men aged 20-55. The goal was simply to measure drug levels in the body, not to …

This small study looked at whether taking aspirin before niacin can reduce the uncomfortable flushing (redness and warmth) that niacin often causes. Nine healthy adults with high cholesterol took either aspirin or a placebo for five days, then a dose of niacin. Researchers measur…

This study looked at how a new drug, HRS-1301, changes the way the body processes rosuvastatin, a common cholesterol-lowering medicine. Sixteen healthy adults took both drugs in a fixed order, and researchers measured drug levels in the blood. The goal was to gather safety and in…

This study looked at how fat particles called lipoproteins travel in the blood. Researchers wanted to better understand normal and abnormal fat metabolism and its link to hardening of the arteries. About 759 healthy volunteers and people with cholesterol disorders took part. Part…

This study followed 514 people with stable coronary artery disease for 18 months to see if how their bodies handle triglycerides (a type of fat) after a meal could predict future heart problems. Researchers also looked at blood sugar control and other health markers. The goal was…