HYPERCORTISOLISM
Clinical trials for HYPERCORTISOLISM explained in plain language.
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New drug shows promise for cortisol disorder in phase 3 trial
Disease control CompletedThis study tested a drug called relacorilant in 137 people with high cortisol levels due to non-cancerous adrenal gland growths. The goal was to see if the drug could improve blood pressure and blood sugar control. Participants received either the drug or a placebo, and researche…
Matched conditions: HYPERCORTISOLISM
Phase: PHASE3 • Sponsor: Corcept Therapeutics • Aim: Disease control
Last updated May 18, 2026 12:12 UTC
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Cortisol-Blocking drug shows promise for blood pressure and sugar control
Disease control CompletedThis study looked at whether metyrapone, a drug that lowers cortisol, can improve health in 20 adults with mild Cushing's syndrome (a condition of high cortisol). Researchers measured changes in blood pressure, blood sugar, cholesterol, and mood over the treatment period. The goa…
Matched conditions: HYPERCORTISOLISM
Sponsor: Istituto Auxologico Italiano • Aim: Disease control
Last updated May 15, 2026 11:54 UTC
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Spit test could spot hormone disorder in adrenal tumor patients
Diagnosis CompletedThis study looked at whether measuring cortisol in saliva works as well as the standard blood test to diagnose high cortisol levels (hypercortisolism) in people with adrenal incidentalomas—non-cancerous tumors found by chance on scans. About 100 patients and 100 healthy adults pr…
Matched conditions: HYPERCORTISOLISM
Sponsor: Rigshospitalet, Denmark • Aim: Diagnosis
Last updated May 26, 2026 04:37 UTC
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Hidden hormone culprit found in many with stubborn high blood pressure
Knowledge-focused CompletedThis study looked at over 1,100 adults in the US with resistant hypertension (high blood pressure that doesn't respond well to treatment) to find out how many also have a condition called endogenous hypercortisolism, where the body makes too much cortisol. Participants provided b…
Matched conditions: HYPERCORTISOLISM
Sponsor: Corcept Therapeutics • Aim: Knowledge-focused
Last updated May 22, 2026 13:51 UTC