HYPERALGESIA
Clinical trials for HYPERALGESIA explained in plain language.
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New combo may stop opioids from making pain worse after surgery
Symptom relief CompletedThis study looked at whether giving ketamine during surgery and methadone after surgery can prevent a condition called opioid-induced hyperalgesia, where painkillers actually make you more sensitive to pain. 113 adults having open colorectal surgery took part. The goal was to see…
Matched conditions: HYPERALGESIA
Phase: NA • Sponsor: Fondazione IRCCS Istituto Nazionale dei Tumori, Milano • Aim: Symptom relief
Last updated May 18, 2026 12:10 UTC
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Laughing gas studied for pain relief in healthy volunteers
Knowledge-focused CompletedThis early-stage study tested whether breathing a mixture of 35% nitrous oxide (laughing gas) can reduce pain sensitivity in 20 healthy men. Researchers used mild electrical stimulation to create temporary pain and measured how well the gas worked. The goal was to understand how …
Matched conditions: HYPERALGESIA
Phase: PHASE1 • Sponsor: Air Liquide Santé International • Aim: Knowledge-focused
Last updated May 26, 2026 11:08 UTC