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Scientists test reliability of pain measures in capsaicin model

NCT ID NCT07625475

Knowledge-focused Sponsor: University of Guelph Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether two common pain tests (temporal summation and offset analgesia) give consistent results when used multiple times in healthy adults. 16 volunteers had capsaicin cream applied to their skin to create temporary sensitivity, then the tests were repeated. The goal was to help researchers choose the best methods for future pain studies, not to treat any disease.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

16 people

The number who actually took part.

Started

May 2024

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy adult volunteers (≥18 years of age) * Able to provide written informed consent in English Exclusion Criteria: * Current or chronic pain * Neurological disease * Skin conditions or sensitivity over the test sites to capsaicin * Contraindications to thermal stimulation of the skin * Musculoskeletal conditions that could alter somatosensory processing * Use of analgesic medications within 24 hours prior to each session * Use of caffeine within 24 hours prior to each session * Use of alcohol within 24 hours prior to each session

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Conditions

The condition(s) this trial relates to.

Hyperalgesia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Central nervous system sensitization Hyperalgesia Pain perception Pain threshold

Contacts and locations

Locations

  • Human Health Sciences, University of Guelph

    Guelph, Ontario, N1G2W1, Canada

More trials for these conditions

Other studies related to the condition(s) this trial covers.