HPV-RELATED MALIGNANCY
Clinical trials for HPV-RELATED MALIGNANCY explained in plain language.
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Supercharged immune cells take on HPV cancers
Disease control Recruiting nowThis study tests a new immunotherapy for people with advanced HPV-related cancers (cervical, throat, anal, and others). Doctors take a patient's own immune cells, add a special receptor to help them find and attack HPV-infected cancer cells, and give them back. The goal is to shr…
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE2 • Sponsor: Christian Hinrichs • Aim: Disease control
Last updated May 26, 2026 09:10 UTC
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New combo therapy aims to revive immune attack on hard-to-treat cervical cancer
Disease control Recruiting nowThis study tests whether adding an experimental drug (PRGN-2009) to the existing immunotherapy pembrolizumab can shrink tumors in people with advanced cervical cancer that no longer responds to pembrolizumab alone. About 24 adults with HPV-positive, recurrent or metastatic cervic…
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE2 • Sponsor: Precigen, Inc • Aim: Disease control
Last updated May 26, 2026 09:00 UTC
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Blood test may spare some HPV throat cancer patients from unnecessary radiation
Disease control Recruiting nowThis study is for people with HPV-related throat cancer who have had or will have surgery to remove the tumor. Researchers will use a blood test to look for tiny bits of cancer DNA (ctDNA) to see if the cancer is likely to come back. The goal is to find out if some patients can s…
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE2 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated May 26, 2026 09:00 UTC
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Immune cells engineered to fight HPV tumors before standard care
Disease control Recruiting nowThis study tests whether a single dose of a patient's own genetically modified immune cells (E7 TCR-T cells) can shrink or eliminate HPV-related cancers before standard treatment like chemo-radiation or surgery. About 15 adults with advanced HPV-positive cancers (e.g., cervical, …
Matched conditions: HPV-RELATED MALIGNANCY
Phase: PHASE1, PHASE2 • Sponsor: Christian Hinrichs • Aim: Disease control
Last updated May 26, 2026 08:33 UTC