HIV-1-INFECTION
Clinical trials for HIV-1-INFECTION explained in plain language.
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HIV drug study halted: PRO 140 monotherapy tested for viral control
Disease control TerminatedThis study looked at whether a drug called PRO 140 could keep HIV under control when used alone (without other HIV meds) over a long period. It included 56 adults with HIV who had already been on PRO 140 for 48 weeks and had undetectable virus levels. The study was stopped early,…
Matched conditions: HIV-1-INFECTION
Phase: PHASE2, PHASE3 • Sponsor: CytoDyn, Inc. • Aim: Disease control
Last updated May 26, 2026 02:57 UTC
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Early HIV drug study stopped short
Disease control TerminatedThis study tested a new experimental HIV medicine, GS-1219, in a small group of 4 people living with HIV-1. The goal was to check if the drug is safe and how well it lowers the amount of virus in the blood. The study was stopped early, so results are very limited.
Matched conditions: HIV-1-INFECTION
Phase: PHASE1 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated May 20, 2026 11:57 UTC
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Weekly HIV pill shows promise but study halted early
Disease control TerminatedThis study tested whether a new once-weekly oral drug combination (lepetegravir and lenacapavir pacfosacil) could control HIV as well as the daily pill Biktarvy in people who had never taken HIV medication before. The trial was terminated early, so results are limited. It involve…
Matched conditions: HIV-1-INFECTION
Phase: PHASE2, PHASE3 • Sponsor: Gilead Sciences • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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Can talking in groups help teens with HIV feel better and take their meds?
Symptom relief TerminatedThis study tested a group-based therapy program for young people living with HIV in low-resource areas. The goal was to see if the program could improve mental health and help them stick to their HIV medication. The study involved 484 participants and used local youth leaders to …
Matched conditions: HIV-1-INFECTION
Phase: NA • Sponsor: International Maternal Pediatric Adolescent AIDS Clinical Trials Group • Aim: Symptom relief
Last updated May 26, 2026 03:03 UTC
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HIV and opioid treatment study halted early – what researchers hoped to learn
Knowledge-focused TerminatedThis study looked at how different medications for opioid use disorder (methadone, buprenorphine, or naltrexone) affect immune system recovery in people with HIV who also inject opioids. Researchers measured markers of immune activation and gut health over 24 weeks. The study was…
Matched conditions: HIV-1-INFECTION
Phase: PHASE2 • Sponsor: University of Pennsylvania • Aim: Knowledge-focused
Last updated May 26, 2026 02:51 UTC