HIGH RISK MYELODYSPLASTIC SYNDROME
Clinical trials for HIGH RISK MYELODYSPLASTIC SYNDROME explained in plain language.
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New combo tackles tough blood cancers in early trial
Disease control OngoingThis study tests a combination of two chemotherapy drugs (CPX-351 and gemtuzumab ozogamicin) in about 50 adults with acute myeloid leukemia (AML) that has returned or not responded to treatment, or with high-risk myelodysplastic syndrome (MDS). The goal is to see if the combinati…
Matched conditions: HIGH RISK MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:42 UTC
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Precision radiation may boost transplant success in blood cancers
Disease control OngoingThis study tests a new radiation technique called total marrow and lymphoid irradiation (TMLI) given before a stem cell transplant from a half-matched donor. The goal is to deliver higher radiation to cancer cells while protecting healthy organs, potentially reducing serious side…
Matched conditions: HIGH RISK MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: City of Hope Medical Center • Aim: Disease control
Last updated May 26, 2026 08:40 UTC
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New hope for older blood cancer patients: smarter transplants on the horizon
Disease control OngoingThis study looks at ways to improve stem cell transplants for older adults with acute myeloid leukemia (AML) or high-risk myelodysplastic syndrome (MDS). It compares different pre-transplant and conditioning therapies to reduce relapse and improve survival. About 333 participants…
Matched conditions: HIGH RISK MYELODYSPLASTIC SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: University of Birmingham • Aim: Disease control
Last updated May 26, 2026 08:33 UTC
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New transplant timing strategy may tame High-Risk blood cancers
Disease control OngoingThis study tests a specific schedule of chemotherapy drugs (busulfan and fludarabine) followed by a donor stem cell transplant for people with high-risk blood cancers like leukemia and lymphoma. After the transplant, a drug called cyclophosphamide is given to help prevent the don…
Matched conditions: HIGH RISK MYELODYSPLASTIC SYNDROME
Phase: PHASE2 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:30 UTC
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New antibody takes aim at Hard-to-Treat blood cancers
Disease control OngoingThis early-phase study tests a new antibody called Hu8F4 in 72 people with advanced blood cancers like leukemia and myelodysplastic syndrome. The main goal is to find a safe dose and check for side effects. Researchers hope the antibody can slow or stop cancer growth.
Matched conditions: HIGH RISK MYELODYSPLASTIC SYNDROME
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 08:19 UTC