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Precision radiation may boost transplant success in blood cancers

NCT ID NCT04262843

First seen Feb 01, 2026 · Last updated May 23, 2026 · Updated 14 times

Summary

This study tests a new radiation technique called total marrow and lymphoid irradiation (TMLI) given before a stem cell transplant from a half-matched donor. The goal is to deliver higher radiation to cancer cells while protecting healthy organs, potentially reducing serious side effects like organ damage and graft-versus-host disease. The trial includes 33 adults with acute leukemia or high-risk myelodysplastic syndrome. Researchers are measuring how well patients survive without relapse or severe complications.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • City of Hope Medical Center

    Duarte, California, 91010, United States

Conditions

Explore the condition pages connected to this study.