High grade serous ovarian cancer
Clinical trials for High grade serous ovarian cancer explained in plain language.
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Can a targeted drug duo hold off ovarian cancer's return?
Disease control Not yet recruitingThis trial tests whether raludotatug deruxtecan, given alone or with bevacizumab, can delay cancer growth better than standard care in people with platinum-sensitive ovarian, primary peritoneal, or fallopian tube cancer that has returned after first treatment. About 600 adults as…
Matched conditions: HIGH GRADE SEROUS OVARIAN CANCER
Phase 3 • Sponsor: Daiichi Sankyo • Aim: Disease control
Last updated Sep 03, 2026 00:00 UTC
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New drug cocktail aims to make ovarian tumors operable
Disease control Not yet recruitingThis study tests whether a combination of two immunotherapy drugs (QL1706), a targeted therapy (bevacizumab), and standard chemotherapy can shrink advanced ovarian cancer before surgery. About 36 women with stage III-IV ovarian cancer will receive the treatment every 3 weeks, the…
Matched conditions: HIGH GRADE SEROUS OVARIAN CANCER
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 14:03 UTC
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Mapping the DNA test that decides who gets PARP inhibitors
Diagnosis Not yet recruitingResearchers are reviewing medical records from about 1,125 women in Italy with newly diagnosed advanced high-grade epithelial ovarian cancer. The study focuses on how hospitals test tumors for homologous recombination deficiency (HRD), a DNA repair flaw that can make PARP inhibit…
Matched conditions: HIGH GRADE SEROUS OVARIAN CANCER
Sponsor: Fondazione Policlinico Universitario Agostino Gemelli IRCCS • Aim: Diagnosis
Last updated Sep 19, 2026 00:00 UTC
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Could a Low-Carb diet boost ovarian cancer therapy?
Knowledge-focused Not yet recruitingThis study examines if different eating patterns, especially low-carbohydrate diets, are linked to better outcomes in women with high-grade serous ovarian cancer who are on maintenance therapy with PARP inhibitors. Researchers will review medical records and survey 600 patients f…
Matched conditions: HIGH GRADE SEROUS OVARIAN CANCER
Sponsor: Tongji Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:02 UTC
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Blood test after surgery could spot hidden cancer cells
Knowledge-focused Not yet recruitingThis study looks at whether a blood test for circulating tumor DNA (ctDNA) can detect leftover cancer after surgery in people with breast, lung, prostate, ovarian, or stomach cancer. About 840 participants will give blood samples before and after standard treatments. No new treat…
Matched conditions: HIGH GRADE SEROUS OVARIAN CANCER
Sponsor: European Institute of Oncology • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC