HEREDITARY SPASTIC PARAPLEGIA
Clinical trials for HEREDITARY SPASTIC PARAPLEGIA explained in plain language.
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Could electrical shocks help weak muscles? new study hopes to find out
Symptom relief Recruiting nowThis study is testing whether whole-body electrical muscle stimulation (WB-EMS) can help adults with neuromuscular diseases like ALS, muscular dystrophy, and myasthenia gravis exercise safely. Because these conditions make normal exercise difficult, WB-EMS uses electrical pulses …
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase: NA • Sponsor: University of Missouri-Columbia • Aim: Symptom relief
Last updated May 26, 2026 06:19 UTC
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Spinal zaps may help stiff legs move freely again
Symptom relief Recruiting nowThis study tests a noninvasive spinal cord stimulation (tSCS) to improve walking and reduce muscle stiffness in 15 adults with hereditary spastic paraplegia (HSP). Participants receive stimulation through skin electrodes on the lower back twice a week for 8 weeks, then are follow…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase: NA • Sponsor: Rahul Sachdeva • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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Researchers launch major effort to track rare nerve disease over time
Knowledge-focused Recruiting nowThis study is for people with certain types of hereditary spastic paraplegia (SPG4 or SPG5A). Researchers will collect medical information, blood samples, and genetic data to build a shared database. The goal is to better understand how the disease progresses and prepare for futu…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 22, 2026 13:53 UTC
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New HSP registry aims to speed up research and future treatments
Knowledge-focused Recruiting nowThis study is creating a registry for people with hereditary spastic paraplegia (HSP), a rare nerve disorder that causes leg stiffness and weakness. Researchers will collect health data, track symptoms over time, and look for new genetic causes. The goal is to better understand t…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: IRCCS Fondazione Stella Maris • Aim: Knowledge-focused
Last updated May 19, 2026 11:48 UTC
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Gene hunt for rare paralysis disorder launches
Knowledge-focused Recruiting nowThis study aims to uncover the genetic causes of hereditary spastic paraplegia (HSP), a group of rare nerve diseases that cause progressive muscle stiffness and disability. Researchers will analyze DNA from 200 children and adults with HSP to find gene variants linked to the cond…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 14, 2026 12:02 UTC
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New study aims to unlock the secrets of rare genetic movement disorder
Knowledge-focused Recruiting nowThis study collects health information and biological samples from up to 700 people under 30 with early-onset hereditary spastic paraplegia (HSP). Researchers hope to better understand how the disease progresses over time. The goal is to create a registry and biorepository to sup…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: Boston Children's Hospital • Aim: Knowledge-focused
Last updated May 13, 2026 15:58 UTC