Hereditary spastic paraplegia
Clinical trials for Hereditary spastic paraplegia explained in plain language.
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One Patient's hope: can an old TB drug help a rare paralysis condition?
Disease control CompletedThis study tested the drug D-cycloserine in a single patient with a rare genetic form of hereditary spastic paraplegia. The goal was to see if the drug is safe and can slow the disease by lowering certain fats (sphingolipids) in the body. The patient also took pyridoxine to help …
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase 4 • Sponsor: Massachusetts General Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New muscle relaxant drug MTR-601 tested in humans for first time
Symptom relief CompletedThis early-stage trial tested a new oral drug called MTR-601 in 89 healthy adults to see if it is safe and how the body processes it. The drug aims to reduce muscle stiffness and spasms, which could help people with conditions like cerebral palsy, multiple sclerosis, or stroke. S…
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Phase 1 • Sponsor: Motric Bio • Aim: Symptom relief
Last updated Jun 27, 2026 13:02 UTC
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Could a dental exam help spot a rare neurological disease?
Knowledge-focused CompletedResearchers at the University of Barcelona are comparing the teeth, jaws, and facial structure of 25 people with hereditary spastic paraplegia (HSP) against 25 people without the condition. They use non-invasive scans and X-rays to measure jaw relationships, tooth alignment, and …
Matched conditions: HEREDITARY SPASTIC PARAPLEGIA
Sponsor: University of Barcelona • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC