HEMATOLOGICAL MALIGNANCIES
Clinical trials for HEMATOLOGICAL MALIGNANCIES explained in plain language.
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New drug after transplant shows promise in reducing deadly complications
Disease control CompletedThis study looked at whether giving the drug cyclophosphamide after a stem cell transplant can help the new cells settle in better and lower the risk of graft-versus-host disease (GVHD), a serious complication. It involved 78 people with blood cancers who received a transplant fr…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Apr 30, 2026 15:52 UTC
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New Two-Step transplant shows promise for tough blood cancers
Disease control CompletedThis study tested a two-step stem cell transplant method for people with high-risk blood cancers like leukemia and lymphoma. The approach uses a drug called cyclophosphamide to lower the risk of graft-versus-host disease (GVHD), a serious side effect. The goal was to see if more …
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University • Aim: Disease control
Last updated Apr 29, 2026 15:15 UTC
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New combo therapy shows promise for tough blood cancers
Disease control CompletedThis study tested a new drug combination (MK-7684A) in 192 people with blood cancers like lymphoma and multiple myeloma that had returned or stopped responding to prior treatments. The goal was to see if the treatment is safe and can shrink tumors. Participants received the drug …
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE2 • Sponsor: Merck Sharp & Dohme LLC • Aim: Disease control
Last updated Apr 29, 2026 15:01 UTC
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Gene-Based drug study aims to personalize cancer treatment
Knowledge-focused CompletedThis early-phase study looked at how the cancer drug belinostat is processed in the body and its safety in 17 patients with advanced solid tumors or blood cancers. Participants were grouped by their UGT1A1 gene type (common or variant) to see if genetic differences affect drug br…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: PHASE1 • Sponsor: Acrotech Biopharma Inc. • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:51 UTC
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PET scans tested for rare fungal infection in blood cancer patients
Knowledge-focused CompletedThis study looked at whether a special PET scan can help doctors decide the best treatment for a rare fungal infection of the liver and spleen. The infection happens in some people with blood cancer or those who had a stem cell transplant. The goal was to see if the scan could tr…
Matched conditions: HEMATOLOGICAL MALIGNANCIES
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Apr 30, 2026 15:50 UTC