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Gene-Based drug study aims to personalize cancer treatment

NCT ID NCT02680795

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 23 times

Summary

This early-phase study looked at how the cancer drug belinostat is processed in the body and its safety in 17 patients with advanced solid tumors or blood cancers. Participants were grouped by their UGT1A1 gene type (common or variant) to see if genetic differences affect drug breakdown. The goal was to gather information for future dosing guidance, not to treat the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Gabrail Cancer Center Research

    Canton, Ohio, 44718, United States

  • John Wayne Cancer Institute @ Providence Saint John's Health Center

    Santa Monica, California, 90404, United States

  • The Oncology Institute of Hope and Innovation

    Whittier, California, 90603, United States

Conditions

Explore the condition pages connected to this study.