HEART VALVE DISEASES

This early study tests a new device called the DUO System for people with a severe leaky tricuspid heart valve. The goal is to see if the device is safe and works well. About 15 adults who still have symptoms despite medical treatment will take part.

This study looks at two ways to deliver cardiac rehabilitation—a program of exercise, education, and counseling for people with heart conditions. One method is in-person at a clinic, the other is done remotely via telehealth. The goal is to see if both approaches are equally effe…

This early study tests a new device called the Topaz system, which replaces the tricuspid heart valve without open-heart surgery. It is for 15 adults with severe tricuspid regurgitation (leaky valve) who are at high risk for surgery. The goal is to see if the device is safe and c…

This study tests a device called the Carillon Mitral Contour System in 300 people with heart failure and a leaky mitral valve. The device is placed in a vein to help the valve close better, aiming to reduce symptoms and hospital stays. Participants are randomly assigned to get th…

This study aims to detect heart valve disease and heart failure in people aged 65 and older from diverse communities. Researchers will train non-expert staff in GP offices to perform quick cardiac ultrasound scans. The goal is to find hidden heart problems early, reduce emergency…

This study tests an artificial intelligence (AI) tool that can screen for heart valve disease using standard chest CT scans that people already get for other reasons. The goal is to catch moderate-to-severe valve problems earlier without extra tests or radiation. Researchers will…

This study tests whether a portable electronic stethoscope, combined with artificial intelligence, can accurately detect valvular heart disease. About 125 people with and without the condition will use the device and also receive standard heart tests. Researchers will compare the…

This study looks at whether giving routine heart ultrasounds to nursing home residents can help catch heart problems early and reduce emergency hospital visits. About 1,050 residents will take part, and researchers will track how well the screening works and if it leads to better…

This study is a large registry that will follow 10,000 people who receive a TAVR procedure to replace a faulty heart valve. The goal is to see how well the procedure works over the long term in everyday medical practice. Researchers will track deaths, heart attacks, and other hea…

This study looks at whether a special heart ultrasound measurement, called global longitudinal strain (GLS), can predict if a person will have a hard time coming off the heart-lung machine during heart surgery. Researchers will follow 213 adults having planned heart surgery and t…