HEART TRANSPLANTATION
Clinical trials for HEART TRANSPLANTATION explained in plain language.
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Could a Once-Daily pill replace Twice-Daily dosing for young transplant patients?
Disease control CompletedThis study tested whether children who had received an organ transplant (kidney, liver, heart, lung, or intestine) could safely switch from taking tacrolimus twice a day (Prograf) to a once-daily version (Advagraf). The goal was to see if the once-daily pill provided similar drug…
Matched conditions: HEART TRANSPLANTATION
Phase: PHASE2 • Sponsor: Astellas Pharma Europe Ltd. • Aim: Disease control
Last updated Jun 23, 2026 19:16 UTC
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Heart transplant hope: simple supplement may boost exercise and kidney health
Disease control CompletedThis study tested whether taking L-arginine supplements for six weeks could improve exercise ability and kidney function in 30 stable heart transplant recipients. The goal was to see if this amino acid could help with common post-transplant problems like poor exercise capacity an…
Matched conditions: HEART TRANSPLANTATION
Phase: PHASE4 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Jun 23, 2026 11:57 UTC
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Heart transplant clock: does donor timing matter?
Knowledge-focused CompletedThis study looked at 200 heart transplant patients to see if the time of day the donor heart was removed affects how well the patient does. Researchers compared hearts taken during the body's rest phase (midnight to noon) versus the active phase (noon to midnight). They tracked s…
Matched conditions: HEART TRANSPLANTATION
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 22, 2026 12:05 UTC
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Beating heart machine tested in transplant study
Knowledge-focused CompletedThis study looked at how well a device called the Organ Care System (OCS) works for preserving donor hearts before transplantation. The OCS keeps the heart in a near-natural, beating state instead of on ice. Researchers followed 93 heart transplant recipients for 12 months to see…
Matched conditions: HEART TRANSPLANTATION
Sponsor: Hannover Medical School • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:59 UTC
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Scientists hunt for simple blood test to predict heart rejection
Knowledge-focused CompletedThis study aims to find substances in blood or urine that can signal when a transplanted heart is being rejected. By analyzing samples from 188 heart transplant patients and healthy volunteers, researchers hope to develop a simple test for early detection. The goal is to catch re…
Matched conditions: HEART TRANSPLANTATION
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:26 UTC