HEART TRANSPLANTATION

This study tests whether belatacept, an anti-rejection medication, is safe for adults who have just received a new heart. About 12 participants will receive the drug and be monitored for serious complications like rejection, infection, or organ failure. The goal is to find a bett…

This study tests a new liquid (Custodiol-N) used to preserve donor hearts before transplant in children. The goal is to see if it is as safe as the current standard solution. Fifteen children awaiting their first heart transplant will take part, and researchers will monitor side …

This study tests whether giving a concentrated saltwater solution (hypertonic saline) right after a heart transplant can prevent or lessen acute kidney injury. About 74 adults who are hospitalized for a heart transplant will take part. The goal is to see if this simple approach c…

This study looks at the long-term health of children (16 years and older) whose mothers had a solid organ transplant before pregnancy. Researchers want to see if these children have higher risks for heart or kidney problems, possibly due to the mother's transplant or medications.…

This study follows 270 heart transplant recipients to track how their heart and body metabolism change over time. Researchers will use imaging, blood tests, and biopsies to monitor heart function, rejection, kidney health, infections, and cancer risk. The goal is to better unders…

This study looks at 683 heart transplant recipients to see if advanced heart scans (CMR) and blood tests can detect early signs of organ rejection. Participants must be stable and at least one year post-transplant. The goal is to find better, less invasive ways to diagnose antibo…

This study looks at how small blood vessels work in people who have had a heart transplant. Researchers will use a non-invasive laser device to measure skin blood flow. The goal is to learn more about heart health after transplant, not to test a new treatment. About 31 participan…

This study is testing a new blood test that looks for DNA from the donor heart to catch early signs of rejection in heart transplant patients. Researchers will compare the test results with standard heart biopsies to see if the blood test is accurate. The goal is to make monitori…

This study will follow 10,000 adults with heart conditions (like heart failure, heart attack, or heart surgery) who are going through a cardiac rehabilitation program in Davos, Switzerland. Researchers will collect health data, blood samples, and patient reports to understand wha…

This study looks at heart tissue samples from 216 adults who already need a biopsy as part of their care. Researchers want to find unique molecular patterns in different heart conditions, including after a heart transplant. The goal is to improve how these diseases are diagnosed …

This study looks at fat cells near the heart's arteries in 60 patients getting a heart transplant. Researchers want to see if the size of these fat cells is linked to immune system changes and heart disease. The goal is to better understand how fat around arteries affects heart h…

This study uses special MRI scans to look at how the heart and muscles work together during exercise in children with heart disease or those who have had a heart transplant. Researchers want to learn more about what affects fitness in these kids. About 20 children aged 10 to 18 w…