HEART TRANSPLANTATION
Clinical trials for HEART TRANSPLANTATION explained in plain language.
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New drug switch for young transplant patients shows promise
Disease control CompletedThis study tested switching children who had stable organ transplants from one immunosuppressant (Prograf) to a longer-acting version (Advagraf). The goal was to compare drug levels in the body and monitor safety and effectiveness over one year, with extended follow-up. 81 childr…
Matched conditions: HEART TRANSPLANTATION
Phase: PHASE2 • Sponsor: Astellas Pharma Europe Ltd. • Aim: Disease control
Last updated Jun 15, 2026 18:57 UTC
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Heart transplant patients may get a boost from a simple supplement
Disease control CompletedThis study looked at whether taking L-arginine, a natural amino acid, for 6 weeks could help heart transplant recipients exercise more easily and improve kidney function. Thirty stable male heart transplant patients took part. The goal was to see if this supplement could address …
Matched conditions: HEART TRANSPLANTATION
Phase: PHASE4 • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated Jun 15, 2026 18:55 UTC
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New heart box keeps donor organs beating during transplant
Knowledge-focused CompletedThis study looked at how a special machine called the Organ Care System (OCS) keeps donor hearts alive outside the body during heart transplants. Researchers followed 93 patients who received a heart transplant using this system. The main goal was to see how many patients were st…
Matched conditions: HEART TRANSPLANTATION
Sponsor: Hannover Medical School • Aim: Knowledge-focused
Last updated Jun 12, 2026 12:04 UTC
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Heart transplant timing may impact survival, new study finds
Knowledge-focused CompletedThis study looked at 200 heart transplant patients to see if the time of day the donor heart was removed affects long-term outcomes. Researchers compared hearts taken during the body's rest phase (midnight to noon) versus the active phase (noon to midnight). They followed patient…
Matched conditions: HEART TRANSPLANTATION
Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:29 UTC
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Scientists hunt for simple blood test to predict heart rejection
Knowledge-focused CompletedThis study aims to find substances in blood or urine that can signal when a transplanted heart is being rejected. By analyzing samples from 188 heart transplant patients and healthy volunteers, researchers hope to develop a simple test for early detection. The goal is to catch re…
Matched conditions: HEART TRANSPLANTATION
Sponsor: National Institutes of Health Clinical Center (CC) • Aim: Knowledge-focused
Last updated Jun 10, 2026 13:26 UTC