HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF) explained in plain language.
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Women's heart failure: quick drug boost may cut hospital returns
Disease control Not yet recruitingThis study tests whether giving women the full recommended doses of heart failure medications quickly after a hospital stay can reduce the risk of death or readmission within a year. About 360 women from 13 Italian hospitals will be randomly assigned to either intensive medicatio…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE4 • Sponsor: IRCCS Policlinico S. Donato • Aim: Disease control
Last updated May 26, 2026 09:53 UTC
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Heart shunt device aims to boost energy and ease strain in failing hearts
Disease control Not yet recruitingThis study tests a small device placed in the heart to create a tiny passage between two upper chambers. The goal is to lower pressure inside the heart, improve its energy use, and help it pump better. The study will include 15 adults with advanced heart failure who are already o…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: NA • Sponsor: Heinrich-Heine University, Duesseldorf • Aim: Disease control
Last updated May 26, 2026 09:49 UTC
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New pill could help failing hearts pump better
Disease control Not yet recruitingThis study tests an experimental oral drug called AC01 in 400 people with chronic advanced heart failure and a weak heart pump. The goal is to see if AC01 improves heart function over 12 weeks compared to a placebo. Participants must have had heart failure for at least 6 months a…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE2 • Sponsor: AnaCardio AB • Aim: Disease control
Last updated May 20, 2026 11:54 UTC
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New heart procedure could ease symptoms of heart failure
Symptom relief Not yet recruitingThis early-stage trial tests a catheter-based procedure that targets a nerve near the heart to see if it can safely improve symptoms in people with heart failure with reduced ejection fraction (HFrEF). Up to 50 patients aged 40 or older will be randomly assigned to receive either…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: NA • Sponsor: Axon Therapies, Inc. • Aim: Symptom relief
Last updated May 19, 2026 12:00 UTC
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New study aims to predict heart failure outcomes using Body's inner clues
Knowledge-focused Not yet recruitingThis study will follow 400 people with chronic heart failure and 200 healthy volunteers for one year. Researchers will collect blood, stool, and imaging data to find patterns that predict who might need to go back to the hospital or die from heart failure. The goal is to build a …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated May 18, 2026 12:07 UTC