HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF) explained in plain language.
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Heart failure drug shows promise for vessel health
Disease control CompletedThis study looked at whether the drug vericiguat can improve blood vessel function, reduce inflammation, and make people with heart failure feel better. 26 adults with heart failure with reduced ejection fraction took vericiguat alongside their standard treatments. Researchers me…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE4 • Sponsor: Josef Stehlik • Aim: Disease control
Last updated May 26, 2026 04:37 UTC
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New heart failure drug passes early safety check
Symptom relief CompletedThis early-stage study tested a new drug called XXB750 in 27 adults with chronic heart failure and reduced heart pumping ability. The main goal was to check if the drug is safe and tolerable. Participants received either the drug or a placebo, and researchers monitored for side e…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Symptom relief
Last updated May 26, 2026 04:30 UTC
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Blood tests may reveal why some heart failure patients develop dangerous rhythms
Knowledge-focused CompletedThis study looked at blood samples from 60 people with heart failure and a history of dangerous heart rhythms. Researchers compared those whose heart failure was caused by blocked arteries versus other causes. The goal was to find unique chemical patterns in the blood that might …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Muhammed Heja Geçit • Aim: Knowledge-focused
Last updated May 26, 2026 04:30 UTC
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Heart failure risk prediction gets a boost from blood and imaging combo
Knowledge-focused CompletedThis study looked at medical records of 4,000 heart failure patients to see if combining routine blood tests (like NT-proBNP) with heart scan results (like fat density around the heart) could better predict who might die within a year. The goal is to improve personalized risk ass…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated May 22, 2026 14:04 UTC