HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Clinical trials for HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF) explained in plain language.
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Heart failure drug tested for hidden benefits beyond the heart
Disease control CompletedThis study tested whether the heart failure drug vericiguat improves the health of blood vessels and reduces body-wide inflammation in patients. It involved 26 adults with chronic heart failure who were already on standard treatments. Researchers measured blood vessel function, w…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE4 • Sponsor: Josef Stehlik • Aim: Disease control
Last updated Apr 03, 2026 14:42 UTC
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Novartis tests new shot for weakened hearts
Disease control CompletedThis early-stage study tested the safety and side effects of a new drug called XXB750 for people with chronic heart failure. It involved 27 participants who received either the drug or a placebo via injection. The main goal was to see how well the drug was tolerated and how it mo…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Phase: PHASE1 • Sponsor: Novartis Pharmaceuticals • Aim: Disease control
Last updated Feb 19, 2026 14:37 UTC
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Scientists search for chemical clues behind deadly heart rhythms
Knowledge-focused CompletedThis study aims to understand the chemical differences in the bodies of heart failure patients who experience dangerous, fast heart rhythms. Researchers will compare 60 patients with two different types of heart muscle disease to see how their metabolism differs. The goal is to l…
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Muhammed Heja Geçit • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:42 UTC
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Scientists mine old data to build smarter heart failure treatment guide
Knowledge-focused CompletedThis study looked back at existing medical data from over 4,000 people with severe heart failure. Researchers analyzed blood tests and treatment records to see if they could find patterns that predict which patients might get worse. The goal is to use this information to build a …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:41 UTC
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Scientists hunt for better clues to predict heart failure survival
Knowledge-focused CompletedThis study looked back at the medical records of 4,000 heart failure patients to see if combining information from common blood tests and heart scans could better predict a patient's risk of dying within one year. The goal is to help doctors make more accurate, personalized risk …
Matched conditions: HEART FAILURE WITH REDUCED EJECTION FRACTION (HFREF)
Sponsor: Xinjiang Medical University • Aim: Knowledge-focused
Last updated Mar 12, 2026 13:52 UTC