Heart failure, diastolic
Clinical trials for Heart failure, diastolic explained in plain language.
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New heart pump could help when diuretics fail in acute heart failure
Disease control Recruiting nowThis study tests a device called Aortix, a small pump placed in the main artery, to help remove excess fluid in people hospitalized with acute heart failure who are not responding well to diuretic medications. About 320 participants will be randomly assigned to receive either the…
Matched conditions: HEART FAILURE, DIASTOLIC
Sponsor: Procyrion • Aim: Disease control
Last updated Aug 27, 2026 00:00 UTC
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Could mounjaro ease heart failure in obesity? new trial investigates
Disease control Recruiting nowThis study will test whether tirzepatide (Mounjaro), a drug used for diabetes and weight loss, can help people with obesity-related heart failure with preserved ejection fraction (HFpEF). Researchers will measure changes in blood volume and body fat in 50 participants over 15 mon…
Matched conditions: HEART FAILURE, DIASTOLIC
Phase 4 • Sponsor: Columbia University • Aim: Disease control
Last updated Aug 26, 2026 00:00 UTC
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New heart failure drug enters first human safety trial
Disease control Recruiting nowThis early-stage trial will test a single dose of a new drug called LY3971297 in 90 people with two types of heart failure: preserved ejection fraction (HFpEF) and reduced ejection fraction (HFrEF). The main goal is to see if the drug is safe and what side effects occur. Particip…
Matched conditions: HEART FAILURE, DIASTOLIC
Phase 1 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Aug 23, 2026 00:00 UTC
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Heart failure fluid battle: which pill works better?
Disease control Recruiting nowThis study tests two water pills—acetazolamide and metolazone—added to standard diuretics in 320 adults hospitalized with acute decompensated heart failure. The goal is to see which drug clears fluid buildup faster and more safely, reducing hospital stays and complications. Parti…
Matched conditions: HEART FAILURE, DIASTOLIC
Sponsor: University of Health Sciences Lahore • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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A simple heart scan may unmask a hidden cause of heart failure
Diagnosis Recruiting nowThis study tests whether a cardiac imaging technique called a PYP scan can detect transthyretin amyloidosis in people aged 65 and older who have heart failure with preserved ejection fraction, also known as diastolic heart failure. The researchers will scan 515 participants to se…
Matched conditions: HEART FAILURE, DIASTOLIC
Sponsor: Massachusetts General Hospital • Aim: Diagnosis
Last updated Sep 03, 2026 00:00 UTC
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Can a tailored trial help heart patients decide on Beta-Blockers?
Knowledge-focused Recruiting nowThis study tests whether a personalized 'N-of-1' trial can help older adults with a type of heart failure (HFpEF) decide if they want to continue or stop taking beta-blockers. Twenty participants will go through periods on and off their beta-blocker, in a random order, to see how…
Matched conditions: HEART FAILURE, DIASTOLIC
Phase 4 • Sponsor: Weill Medical College of Cornell University • Aim: Knowledge-focused
Last updated Aug 23, 2026 00:00 UTC
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Scientists probe mouth germs for clues to heart and muscle health
Knowledge-focused Recruiting nowThis observational study looks at how fitness level relates to bacteria in the mouth and blood flow to muscles. Researchers will collect mouth swabs, saliva, and blood samples, and measure exercise capacity in 70 adults with heart failure, peripheral artery disease, or overweight…
Matched conditions: HEART FAILURE, DIASTOLIC
Sponsor: University of Virginia • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Psoriasis patients may face hidden heart dangers, new study aims to find out
Knowledge-focused Recruiting nowThis study is tracking 1,000 adults with psoriasis to see how their skin condition relates to heart disease. Researchers will use blood tests and heart imaging to find early signs of heart problems. The goal is to better understand why people with psoriasis have higher rates of h…
Matched conditions: HEART FAILURE, DIASTOLIC
Sponsor: Herlev and Gentofte Hospital • Aim: Knowledge-focused
Last updated Jun 26, 2026 17:09 UTC