HEART FAILURE, DIASTOLIC

This study tests a device called Aortix, which is a small pump placed in the body to help the heart and kidneys remove excess fluid. It is for people hospitalized with worsening heart failure who still have fluid buildup despite taking strong water pills. About 320 participants w…

This study tests whether a 12-week low-calorie diet can improve heart function, reduce symptoms like breathlessness, and increase exercise ability in people with heart failure with preserved ejection fraction (HFpEF) who also have obesity or type 2 diabetes. About 63 adults will …

This study tests whether adding acetazolamide or metolazone to standard diuretic therapy helps people with acute decompensated heart failure get rid of excess fluid faster and leave the hospital sooner. About 320 adults with severe fluid overload will be randomly assigned to one …

This study is looking at whether people with psoriasis have a higher risk of heart disease. Researchers will follow 1,000 adults with psoriasis, using heart scans and blood tests to find early warning signs. The goal is to better understand the link between psoriasis and heart pr…

This study looks at how your fitness level relates to the bacteria in your mouth and how well blood flows to your muscles. Researchers will collect mouth swabs, saliva, and have participants do a cycling test. The goal is to understand these connections in people with heart failu…