HEADACHE DISORDERS

This study tests whether adding a daily pill (amitriptyline) to online cognitive behavioral therapy (CBT) works better than CBT alone for preventing migraines in children aged 7-17. Researchers will track headache days and disability over time. The goal is to find the best first-…

This study tests a new group therapy program for teens aged 13-17 with migraine. The program combines high-intensity interval training, progressive muscle relaxation, and education sessions over 18 weeks. Researchers want to see if it reduces how often migraines happen, how long …

This study is testing a mind-body program delivered by nurses to help children and teens with migraine have fewer headache days. The program combines different treatment parts to find the best approach. About 260 kids with migraine will take part. The goal is to see if this progr…

This study tests a lifestyle behavior program to help people with chronic migraine reduce how often and how severely their headaches happen. Researchers will also look for biological markers linked to improvement. The goal is to see if the program is practical and liked by partic…

This study looks at whether a 16-week supervised aerobic exercise program, combined with a session on pain education, can help women aged 18 to 48 who have migraines. Researchers will measure changes in headache-related disability, pain sensitivity, and quality of life. The goal …

This study tests whether a scalp block (a numbing injection in the scalp) can reduce severe headaches in people who have had a brain bleed from a burst aneurysm. About 22 adults in intensive care will receive either the scalp block plus standard care or standard care alone. The m…

This study looks at how thinking skills, personality traits, and pain sensitivity affect people with chronic or episodic headaches. Researchers will follow 64 adults for about six months to understand what helps or hinders treatment. The goal is to improve care and prevent headac…

This study looks at how the mind and body respond to migraine treatments, including placebos. Researchers will give 60 adults with chronic migraine four different treatment conditions in random order. The goal is to better understand how expectations and side effects influence tr…