GLIOSARCOMA
Clinical trials for GLIOSARCOMA explained in plain language.
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New hope for glioblastoma? early trial combines targeted drug with radiation
Disease control Recruiting nowThis early-phase study tests a new drug called Peposertib alongside radiation and chemotherapy for people with a fast-growing brain cancer (glioblastoma). The goal is to find the safest dose and see if the drug reaches the brain. About 29 adults with newly diagnosed or returning …
Matched conditions: GLIOSARCOMA
Phase: PHASE1 • Sponsor: M.D. Anderson Cancer Center • Aim: Disease control
Last updated May 26, 2026 11:20 UTC
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Brain tumor patients get virus-immunotherapy combo in new trial
Disease control Recruiting nowThis study tests a treatment for people with aggressive brain tumors (glioblastoma, anaplastic astrocytoma, or gliosarcoma) that have come back or are newly diagnosed. The treatment combines a genetically modified herpes virus (M032) that delivers an immune-boosting protein (IL-1…
Matched conditions: GLIOSARCOMA
Phase: PHASE1, PHASE2 • Sponsor: University of Alabama at Birmingham • Aim: Disease control
Last updated May 26, 2026 11:20 UTC
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New hope for recurrent brain cancer? drug combo enters human testing
Disease control Recruiting nowThis early-phase study tests a new two-drug combination for adults whose high-grade glioma (a type of brain cancer) has come back after standard treatment. The drugs are a low, continuous dose of temozolomide (a chemotherapy pill) plus abexinostat (an experimental drug). The main…
Matched conditions: GLIOSARCOMA
Phase: PHASE1 • Sponsor: University of Nebraska • Aim: Disease control
Last updated May 22, 2026 13:53 UTC
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Sound waves unlock Brain's defenses against deadly tumor
Disease control Recruiting nowThis study tests a new approach for people with a recently diagnosed aggressive brain cancer called glioblastoma. A device with 9 ultrasound emitters is implanted in the skull to temporarily open the blood-brain barrier, allowing immune-boosting drugs to reach the tumor more effe…
Matched conditions: GLIOSARCOMA
Phase: PHASE2 • Sponsor: Northwestern University • Aim: Disease control
Last updated May 18, 2026 11:59 UTC
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New combo therapy targets deadly brain cancer in early trial
Disease control Recruiting nowThis early-stage study tests whether two experimental drugs, ABBV-637 and ABBV-155, are safe when given alone or with another drug called ERAS-801 for people whose glioblastoma has come back. About 60 adults with a specific type of brain tumor (EGFR gene amplified) will take part…
Matched conditions: GLIOSARCOMA
Phase: PHASE1 • Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Disease control
Last updated Apr 26, 2026 19:38 UTC
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Brain tumor tissue study could unlock new treatments
Knowledge-focused Recruiting nowThis study collects samples of glioblastoma (a type of brain tumor) and blood from 120 adults during standard surgery. Researchers will examine tissue from different parts of the same tumor to see how they differ. The goal is to learn more about the tumor's structure and behavior…
Matched conditions: GLIOSARCOMA
Sponsor: Baptist Health South Florida • Aim: Knowledge-focused
Last updated May 18, 2026 12:13 UTC