GASTROESOPHAGEAL REFLUX DISEASE
Clinical trials for GASTROESOPHAGEAL REFLUX DISEASE explained in plain language.
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Simple surgical addition may ease heartburn after Weight-Loss surgery
Disease control CompletedThis study looked at whether adding a small repair for acid reflux during weight-loss surgery can reduce heartburn symptoms afterward. Fifty adults with severe obesity but no hiatal hernia were split into two groups: one got standard sleeve gastrectomy, the other got the same sur…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Phase: NA • Sponsor: Van Training and Research Hospital • Aim: Disease control
Last updated May 26, 2026 03:25 UTC
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New GERD drug shows symptom relief in large study
Symptom relief CompletedThis study observed over 2,800 adults with erosive gastroesophageal reflux disease (GERD) who took FEXUCLUE tablets. Researchers measured how much heartburn and reflux symptoms improved after 4 to 8 weeks using patient questionnaires. The goal was to see if the drug eases discomf…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Sponsor: Daewoong Pharmaceutical Co. LTD. • Aim: Symptom relief
Last updated May 26, 2026 03:25 UTC
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Heartburn relief without more acid pills? new study tests brain drugs
Symptom relief CompletedThis study tested whether medications that affect the gut-brain connection can relieve symptoms in people with gastroesophageal reflux disease (GERD) who still have problems despite taking standard acid-reducing drugs. Researchers enrolled 164 adults with GERD and gave them a gut…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Phase: NA • Sponsor: RenJi Hospital • Aim: Symptom relief
Last updated May 26, 2026 03:10 UTC
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Xiamen GERD study reveals key risk factors
Knowledge-focused CompletedThis study aimed to find out how common gastroesophageal reflux disease (GERD) is in Xiamen, China, and what factors might increase a person's risk. Researchers looked at 1,625 adults who had typical reflux symptoms like heartburn. The goal was to better understand the disease in…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Sponsor: Zhongshan Hospital (Xiamen), Fudan University • Aim: Knowledge-focused
Last updated May 26, 2026 03:27 UTC
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Constipation drugs may reveal new clues about gut health in Barrett's esophagus patients
Knowledge-focused CompletedThis early study looked at whether two FDA-approved constipation drugs, plecanatide and linaclotide, change levels of a chemical called cGMP in the small intestine. Researchers compared tissue samples from 43 adults with Barrett esophagus or GERD who took one of the drugs or no d…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Phase: PHASE1 • Sponsor: University of Wisconsin, Madison • Aim: Knowledge-focused
Last updated May 26, 2026 03:15 UTC
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Why are we missing early warning signs for esophageal cancer?
Knowledge-focused CompletedThis study looked at why doctors and patients skip screening for Barrett's esophagus, a condition that can lead to esophageal cancer. Researchers surveyed over 700 doctors and patients at seven U.S. health centers to identify knowledge gaps and barriers. The goal is to improve sc…
Matched conditions: GASTROESOPHAGEAL REFLUX DISEASE
Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated May 26, 2026 03:10 UTC