Survey aims to uncover hidden barriers to esophageal cancer screening
NCT ID NCT04408105
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This completed study surveyed over 700 primary care doctors, gastroenterologists, and patients across seven U.S. health systems. The goal was to find out what knowledge gaps, attitudes, and practical barriers prevent people from getting screened for Barrett's esophagus, a condition that can lead to esophageal cancer. By identifying these obstacles, researchers hope to design better screening programs in the future.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could point to better ways to encourage screening for Barrett's esophagus, potentially catching esophageal cancer earlier.
- What could go wrong
- This is an observational survey study, not a treatment trial. It identifies barriers but does not test any intervention, so its direct impact on patient outcomes is uncertain.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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725 people
The number who actually took part.
- Started
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Feb 2020
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
1. We will include patients with a diagnosis of gastroesophageal reflux disease (GERD) who have at least one outpatient clinic visit at a participating site. Patients will be identified through an administrative query of the electronic medical record by ICD-10 codes for GERD (K21.0 and K21.9) as well as through a review of the upcoming clinic schedule. Patients with prior diagnosis of BE/EAC or language other than English will be excluded. Across the 7 sites, we plan to enroll 500 patients. 2. This study will include PCPs and gastroenterologists at participating sites. Across the 7 participating centers, we plan to enroll 100 gastroenterologists and 400 PCPs.
- Ages
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18 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
1. Patient Eligibility Criteria Inclusion Criteria: * Patients identified by ICD-10 codes for GERD (K21.0 and K21.9) AND * Have had at least one outpatient clinic visit at a participating site Exclusion Criteria: * Prior diagnosis of BE/EAC * Non-English speaking 2. Provider Eligibility Criteria Inclusion Criteria: * Provider must be a PCP and/or gastroenterologist AND * Must be at a participating site
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Denver Health Medical Center
Aurora, Colorado, 80045, United States
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Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States
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Parkland Health and Hospital System
Dallas, Texas, 75235, United States
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Pennsylvania Hospital
Philadelphia, Pennsylvania, 19104, United States
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Pennsylvania Presbyterian Hospital
Philadelphia, Pennsylvania, 19104, United States
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University of Colorado Hospital
Aurora, Colorado, 80045, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could patient tissue samples unlock new treatments for gut diseases?
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- Can a swallowed balloon unlock the genetic secrets of esophageal cancer?