GASTROESOPHAGEAL REFLUX

This program provides access to the drug domperidone for young people aged 12-21 who have severe gastroparesis (stomach paralysis) or GERD that hasn't improved with standard treatments. Participants take the medication four times daily and are closely monitored with regular heart…

This study aims to find out which treatment works better for infants with troublesome acid reflux: a cow-milk-protein-free diet or a common acid-reducing medication called omeprazole. It will involve 96 babies under one year old who have frequent reflux episodes and other symptom…

This study is testing a new, simpler way to find Barrett's esophagus, a condition that can lead to a deadly type of esophageal cancer. Researchers want to see if a swallowable balloon device (EsoCheck) and a lab test (EsoGuard) can effectively screen people over 50 who are at ris…

This study is testing whether a soft band worn around the neck can help reduce nighttime acid reflux symptoms. Researchers want to see if gentle external pressure can prevent stomach acid from rising into the throat during sleep. The study will involve 350 adults who continue to …

This study is looking at how well an over-the-counter chewable tablet called Talcid works to relieve heartburn and other stomach symptoms. These symptoms can flare up when people stop taking certain long-term prescription acid-reducing medications (PPIs). About 167 adults in Germ…

This study aims to predict which patients will develop acid reflux after sleeve gastrectomy weight loss surgery. Researchers will use a special measurement tool during an endoscopy procedure before surgery to take measurements. They'll follow patients for up to 5 years to see if …

This study aims to understand if common heartburn medications (proton pump inhibitors) can lead to an overgrowth of bacteria in the small intestine, a condition called SIBO. Researchers will recruit 50 adults with heartburn symptoms who haven't taken these medications recently. P…