FTD
Clinical trials for FTD explained in plain language.
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New gene therapy targets inherited dementia in early trial
Disease control OngoingThis study tests a single dose of a gene therapy called PBFT02 in 30 adults with frontotemporal dementia caused by specific gene mutations. The treatment aims to deliver a working copy of the GRN gene to the brain to help control the disease. Researchers are primarily checking sa…
Matched conditions: FTD
Phase: PHASE1, PHASE2 • Sponsor: Passage Bio, Inc. • Aim: Disease control
Last updated May 20, 2026 11:58 UTC
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Simple blood draws from home could predict dementia years before symptoms
Knowledge-focused OngoingThis study collects blood samples every 3 months for 3 years from people who carry gene mutations linked to frontotemporal dementia (FTD), a brain disease that affects personality and language. The goal is to see if a protein called neurofilament light chain (NfL) changes over ti…
Matched conditions: FTD
Sponsor: The Bluefield Project to Cure Frontotemporal Dementia • Aim: Knowledge-focused
Last updated May 26, 2026 06:05 UTC
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Mayo clinic launches major study to track brain disease progression
Knowledge-focused ENROLLING_BY_INVITATIONThis study aims to learn more about diseases that affect the brain, such as Parkinson's disease and different types of dementia. Researchers will follow 500 adults with symptoms of these conditions, using yearly brain scans and other tests to see how the diseases change over time…
Matched conditions: FTD
Sponsor: Mayo Clinic • Aim: Knowledge-focused
Last updated May 22, 2026 14:03 UTC
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Wearable sensors could help track rare brain diseases from home
Knowledge-focused OngoingThis study is testing a wearable sensor system to remotely monitor movement symptoms in people with Progressive Supranuclear Palsy (PSP) and related disorders. About 60 participants will wear a pendant sensor for 12 months to see if it's a practical way to track disease progressi…
Matched conditions: FTD
Sponsor: Massachusetts General Hospital • Aim: Knowledge-focused
Last updated May 20, 2026 11:57 UTC