FTD
Clinical trials for FTD explained in plain language.
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Gene therapy infused directly into brain aims to halt rare dementia
Disease control Recruiting nowThis early-phase trial tests a gene therapy called AVB-101 for people with frontotemporal dementia caused by GRN gene mutations. The therapy delivers a working copy of the GRN gene directly into the brain during a one-time procedure. The study will enroll 18 adults aged 30-75 to …
Matched conditions: FTD
Phase: PHASE1, PHASE2 • Sponsor: AviadoBio Ltd • Aim: Disease control
Last updated Jun 27, 2026 12:06 UTC
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Zap your brain to sharper thinking? new trial tests TIS for memory loss
Symptom relief Recruiting nowThis study tests a non-invasive brain stimulation technique called temporal interference stimulation (TIS) to see if it can improve cognitive function in people with mild cognitive impairment or early Alzheimer's disease. Sixty participants will receive either real TIS or a sham …
Matched conditions: FTD
Phase: NA • Sponsor: Tianjin Huanhu Hospital • Aim: Symptom relief
Last updated Jun 27, 2026 13:08 UTC
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Can magnetic pulses ease frontotemporal dementia?
Symptom relief Recruiting nowThis study is testing whether a safe, non-invasive brain stimulation technique called rTMS can help people with frontotemporal dementia (FTLD) or those at risk. 120 participants will receive either real or placebo stimulation for 2 weeks, then all will get real stimulation. Resea…
Matched conditions: FTD
Phase: NA • Sponsor: Università degli Studi di Brescia • Aim: Symptom relief
Last updated Jun 27, 2026 08:08 UTC
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Scientists hunt for hidden signs of ALS and FTD in skin and tears
Knowledge-focused Recruiting nowThis study aims to find biological markers (biosignatures) in people with ALS and FTD to make diagnosis more precise. Researchers will analyze samples like spinal fluid, skin, and tears from 230 participants using advanced techniques. The goal is to create a 'disease fingerprint'…
Matched conditions: FTD
Sponsor: Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:02 UTC
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Scientists hunt for hidden biomarkers in brain diseases
Knowledge-focused Recruiting nowThis study aims to find new biological markers for neurodegenerative diseases like Alzheimer's, Parkinson's, and ALS. Researchers will analyze genetic, protein, and metabolic data from 1,200 patients to improve diagnosis, predict disease course, and monitor treatment response. Th…
Matched conditions: FTD
Sponsor: Ospedale Policlinico San Martino • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:59 UTC