FRAGILE X SYNDROME
Clinical trials for FRAGILE X SYNDROME explained in plain language.
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New hope for fragile x: 4-Year drug safety trial launches
Disease control OngoingThis study looks at the long-term safety of a drug called BPN14770 in people with Fragile X syndrome. It is for those who have already completed a previous BPN14770 trial. About 314 adults and teens will take the drug for up to 4 years to see if it is safe and tolerable over time…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE3 • Sponsor: Tetra Discovery Partners • Aim: Disease control
Last updated May 18, 2026 12:03 UTC
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Can an ADHD drug sharpen thinking in kids with intellectual disabilities?
Symptom relief ENROLLING_BY_INVITATIONThis study looks at whether a liquid ADHD medication (methylphenidate) can improve thinking skills in children aged 6 to 17 who have both an intellectual disability and ADHD. The 68 participants will receive either the drug or a placebo, then switch after a break. Researchers wil…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE1 • Sponsor: University of California, Davis • Aim: Symptom relief
Last updated May 26, 2026 07:50 UTC
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CBD gel shows promise for fragile x in Long-Term trial
Symptom relief ENROLLING_BY_INVITATIONThis study looks at the long-term safety of a CBD gel (ZYN002) applied to the skin for children, teens, and young adults with Fragile X syndrome. Participants apply the gel twice daily for 52 weeks. The goal is to see if the gel is safe and helps with symptoms over time.
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: Zynerba Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated May 18, 2026 11:59 UTC
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Brain wave study tests three drugs in fragile x adults
Knowledge-focused OngoingThis study looks at how single doses of baclofen, roflumilast, and memantine affect brain activity and behavior in 45 adults with Fragile X syndrome. Participants take one dose of each drug or a placebo on separate days. The goal is to measure changes in brain waves and clinical …
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2 • Sponsor: Children's Hospital Medical Center, Cincinnati • Aim: Knowledge-focused
Last updated May 26, 2026 07:54 UTC