FRAGILE X SYNDROME
Clinical trials for FRAGILE X SYNDROME explained in plain language.
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CBD gel shows promise for fragile x behaviors in major trial
Symptom relief CompletedThis study tested a CBD gel (ZYN002) applied to the skin in children, teens, and young adults with Fragile X Syndrome. The goal was to see if it could ease behavioral symptoms like irritability and social withdrawal. The trial involved 215 participants and lasted up to 18 weeks, …
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE3 • Sponsor: Zynerba Pharmaceuticals, Inc. • Aim: Symptom relief
Last updated May 26, 2026 04:36 UTC
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Diabetes drug shows promise for fragile x symptoms in new trial
Symptom relief CompletedThis study tested whether metformin, a common diabetes medicine, can help improve language, behavior, and weight problems in people with fragile X syndrome. 125 people aged 6 to 35 took either metformin or a placebo for 4 months. Researchers measured changes in spoken language an…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2 • Sponsor: University of Alberta • Aim: Symptom relief
Last updated May 20, 2026 11:57 UTC
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New drug shows promise for fragile x teens in landmark trial
Symptom relief CompletedThis study tested an experimental drug called BPN14770 in 163 teenage boys with Fragile X syndrome. The goal was to see if the drug could improve thinking skills and daily life abilities compared to a placebo. The trial had two parts: first to check how the drug moves through the…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2, PHASE3 • Sponsor: Tetra Discovery Partners • Aim: Symptom relief
Last updated May 15, 2026 11:56 UTC
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NIH study looks at kids with genetic conditions to sharpen research skills
Knowledge-focused CompletedThis study enrolled 96 children of any age with known or suspected genetic disorders. The main goal was to give clinic staff hands-on experience and explore new research methods, not to provide treatment. Participants had medical exams, lab tests, and sometimes imaging or genetic…
Matched conditions: FRAGILE X SYNDROME
Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) • Aim: Knowledge-focused
Last updated May 26, 2026 05:25 UTC
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Fragile x drug study explores brain waves and home testing
Knowledge-focused CompletedThis study tested a single dose of gaboxadol in 10 adult men with Fragile X syndrome to see how it affects brain activity measured by EEG. Participants took either the drug or a placebo at home and in the clinic. The main goal was to understand how the drug works in the brain and…
Matched conditions: FRAGILE X SYNDROME
Phase: PHASE2 • Sponsor: Craig Erickson • Aim: Knowledge-focused
Last updated May 18, 2026 12:01 UTC