Executive dysfunction

This study looks at two different sedative medicines given to children on breathing machines in the ICU. The goal is to see which one causes less confusion (delirium) and helps the brain recover better. About 372 children up to age 11 will take part. The results could change how …

This trial tests whether a personalized training program called 'Kleuter Extra' can improve executive functioning—skills like attention, self-control, and planning—in preschoolers aged 4 to 6 who have severe congenital heart disease. Many children with this condition face thinkin…

This study tests if teaching children and parents about avoiding certain chemicals (like BPA) can actually lower the levels found in kids' urine. About 700 children aged 6 to 8 in Belgium and Spain will take part in a school program over two and a half years. The goal is to see i…

This study tests whether a 20-week program of exercise alone or exercise combined with cognitive training can improve thinking and memory in breast cancer survivors. 108 women who have finished primary treatment will be assigned to one of three groups: dual-task training, exercis…

This study tests whether a 16-session program called HOPS can help 6th to 8th graders with ADHD improve their organization, time management, and planning skills. Researchers are working with 240 students and their teachers in real school settings to see if the program works outsi…

This study looks at how thinking skills (called executive functions) relate to everyday activities like self-care and play in children with Duchenne muscular dystrophy (DMD). Researchers will compare 38 children with DMD to healthy children using surveys and functional tests. The…

This study looks at whether a group therapy program called Unstuck & On Target can improve flexibility and learning in 64 teens with autism aged 14-18. Researchers will use brain scans (MRI) to see if the therapy changes how the brain processes new information. The goal is to und…

This study looks at whether people with atrial fibrillation (AF) have temporary drops in thinking skills during an AF episode. Researchers will test 600 patients using tablet-based games that measure memory, attention, and decision-making while in AF and again after their heart r…