ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Clinical trials for ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER explained in plain language.
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New hope for seniors with breast cancer: safer combo therapy shows promise
Disease control CompletedThis study looked at how well older adults (70+) with advanced, hormone-positive breast cancer tolerate a combination of palbociclib plus either letrozole or fulvestrant. The goal was to understand side effects and find factors that might predict who handles treatment better. 93 …
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Alliance for Clinical Trials in Oncology • Aim: Disease control
Last updated May 26, 2026 04:20 UTC
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New combo therapy may keep breast cancer from coming back
Disease control CompletedThis study tested whether adding ovarian suppression (stopping the ovaries from making estrogen) and switching to a different hormone drug (exemestane) could better prevent breast cancer from returning in premenopausal women with hormone-sensitive breast cancer. Over 3,000 women …
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: PHASE3 • Sponsor: ETOP IBCSG Partners Foundation • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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New drug combo shows promise for controlling advanced breast cancer
Disease control CompletedThis study tested a combination of two drugs, palbociclib and tamoxifen, as a first treatment for women with a certain type of advanced breast cancer (HR+/HER2-). The goal was to see how long the cancer could be kept from growing. 49 women took part, and the study measured how lo…
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: PHASE2 • Sponsor: Oana Danciu, MD • Aim: Disease control
Last updated May 19, 2026 11:47 UTC
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Shrinking tumors before surgery: a gentler approach to breast cancer?
Symptom relief CompletedThis study tested whether giving a high dose of focused radiation to the tumor before surgery is a safe and effective approach for older patients with early-stage, hormone-sensitive breast cancer. The goal was to shrink the tumor and reduce the amount of healthy tissue removed du…
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: NA • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Symptom relief
Last updated May 20, 2026 11:56 UTC
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Keto diet plus breast cancer drug shows promise in small study
Symptom relief CompletedThis early-phase study tested whether a very low-carbohydrate ketogenic diet taken for two weeks alongside the drug letrozole is feasible and tolerable for people with early-stage, estrogen receptor-positive (ER+) breast cancer. Thirty-one postmenopausal participants followed the…
Matched conditions: ESTROGEN-RECEPTOR-POSITIVE BREAST CANCER
Phase: EARLY_PHASE1 • Sponsor: Vanderbilt-Ingram Cancer Center • Aim: Symptom relief
Last updated May 19, 2026 11:47 UTC