ERECTILE DYSFUNCTION

This Mayo Clinic study tests whether adding low-intensity shockwave therapy to Xiaflex injections can further reduce penile curvature in men with Peyronie's disease. Sixty men with stable symptoms and curvature between 30 and 90 degrees will receive both treatments. The goal is t…

This study is a safety follow-up for 32 men who previously received an experimental stem cell treatment (Cellgram-ED) for erectile dysfunction after prostate removal due to cancer. Researchers are monitoring tumor markers, serious side effects, and any cancer recurrence over time…

This study is testing a new inflatable penile implant called Rigicon Infla10 for men with erectile dysfunction. About 182 men will get the implant and be followed for up to 3 years. The goal is to see if the device is safe and can provide a firm enough erection for sex.

This study looks at whether adding regular exercise (treadmill walking) to vitamin D supplements can improve erectile function in men with type 2 diabetes who also have low vitamin D. Forty men will take vitamin D every two weeks for 12 weeks; half will also walk three times a we…

This study tests whether L-citrulline, a natural supplement, works as well as the drug tadalafil for mild to moderate erectile dysfunction. It also tests if taking both together is better than either alone. 133 men will take one of three treatments for 12 weeks, and researchers w…

This study tests whether an 8-week pelvic floor exercise program can improve erectile dysfunction and premature ejaculation in men aged 25-45. Half of the 50 participants will do the exercises three times a week, while the other half receives standard medical care. Researchers wi…

This study compares two methods to help men regain erectile function after prostate cancer surgery. About 224 men who had surgery within the past 9 months will take part. The goal is to see which approach works better for sexual rehabilitation.

This study is testing whether pelvic floor therapy—a mix of exercises, biofeedback, and mild electrical stimulation—can help men with erectile dysfunction and/or premature ejaculation. Sixty-six men will be split into three groups based on their condition and will receive the the…

This early-stage study tests whether taking a new liquid form of sildenafil (Hezkue Turbo®) with food changes how the body absorbs it compared to taking it on an empty stomach. Twelve healthy men aged 20 to 70 will each receive a 100 mg dose under both conditions. The goal is to …

This study looks at whether using a penile traction device (RestoreX) for several weeks before getting a penile implant can increase the size of the implant and improve patient satisfaction. About 48 men with erectile dysfunction will be randomly assigned to use the device or not…

This study tests a device that delivers gentle shockwaves to the penis to help men with erectile dysfunction (ED). Researchers want to find out which patients see real improvement after treatment. About 157 men with ED will receive the therapy and be followed for 3 months. The go…

This pilot study tests a non-invasive 3D-printed external device to help men with erectile dysfunction achieve satisfactory sexual intercourse. Nine men with moderate to severe ED from any cause, along with their female partners, will try the device. The goal is to see if it is s…

This study tests a device called VERTICA® that uses radio frequency energy to treat erectile dysfunction (ED). About 98 men with mild to moderate ED will use the device at home for 6 months, either the real device or a sham version. The goal is to see if the device improves erect…

This study tests if focused or radial shockwave therapy can improve erectile dysfunction and chronic pelvic pain better than a fake (sham) treatment. It includes 186 men, some with a history of prostate cancer. Participants will receive several sessions of shockwave or sham thera…

This study looks at whether eating a plant-based or animal-based diet changes erection quality in healthy men who already have normal erectile function. About 46 men will eat special meals and have their nighttime erections measured with a device. The goal is to learn how diet mi…

This study looks at whether a single meal of plant-based meat changes nighttime erections compared to a meal of animal meat. Thirty healthy men with normal erectile function will eat each type of meat on separate nights. Their erection quality is measured overnight using a specia…

This study looks at how well blood vessels work in men aged 30–50 with erectile dysfunction or low testosterone. Researchers use a device called EndoPAT to measure vessel function before and 3–6 months after starting standard treatments like daily ED medication or testosterone th…