END STAGE KIDNEY DISEASE (ESRD)

This study tests a new device that widens veins before creating a dialysis access point (fistula) in people with end-stage kidney disease. About 160 adults will either get the device plus standard fistula creation or standard care alone. The goal is to see if the device helps vei…

This study tests a new type of artificial blood vessel (STARgraft) for people with end-stage kidney disease who need dialysis. The graft is placed in the arm to allow blood to flow smoothly for treatment. Researchers will check if it stays open and works well without extra proced…

This study tests whether a type of water pill (thiazide diuretic) can lower blood pressure in people on peritoneal dialysis who have high blood pressure. About 40 participants will take the medication and have their blood pressure, weight, and body fluid levels monitored. The goa…

This study aims to find better ways to treat depression in people with chronic kidney disease (CKD). About 201 adults with advanced CKD and major depression will receive either behavioral activation therapy, a different antidepressant (bupropion), or a placebo, with the option to…

This study looks at whether a plant-focused diet can improve nutrition in adults with end-stage kidney disease who are on peritoneal dialysis and are malnourished. About 100 participants will be randomly assigned to either a plant-focused diet or a standard kidney diet and follow…

This study tests a special scale that measures heart signals to predict when people on peritoneal dialysis might have too much fluid in their body. The goal is to see if the scale can give early warnings, reducing emergency visits and hospital stays. About 125 adults will use the…