EMPHYSEMA OR COPD

This study tests if a lung transplant followed by a bone marrow transplant can help people with end-stage lung disease (like pulmonary fibrosis or COPD) who also have bone marrow failure. The goal is to first fix the lungs, then restore healthy blood cell production. The trial is…

This study tests a foam called AeriSeal in 200 people with severe emphysema who currently cannot get a lung valve because of air leaks in their lungs. The foam is placed in the lung to seal those leaks, allowing doctors to then insert a valve to reduce trapped air and improve bre…

This study tests whether combining a surgical procedure to complete the fissures between lung lobes with standard valve placement can improve outcomes for people with severe emphysema or COPD. About 20 participants will be randomly assigned to either the combined procedure or med…

This study tests a new device called an implantable artificial bronchus (IAB) for people with severe emphysema or COPD. The goal is to see if the device can improve lung function and make breathing easier. About 60 adults will take part, and the main results will be checked 90 da…

This study tests a surgery to complete the fissures (natural separations) between lung lobes in people with severe emphysema or COPD. It is for patients who did not improve after a less invasive valve treatment. The surgery aims to reduce air leaks and improve breathing. About 20…

This study looks at people with a specific genetic form of alpha-1 antitrypsin deficiency (PiMZ) who also have COPD or emphysema. Researchers will use CT scans and blood tests over three years to track how lung density changes. The goal is to find better ways to measure disease p…

This study aims to better understand the physical causes of certain patterns seen on lung ultrasound images in people with interstitial lung disease or COPD. Researchers will compare ultrasound findings with CT scans in 25 patients to link artifacts to specific lung changes. The …