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New study aims to uncover hidden lung damage in genetic disorder

NCT ID NCT06505603

First seen Jan 25, 2026 · Last updated May 23, 2026 · Updated 18 times

Summary

This study looks at people with a specific genetic form of alpha-1 antitrypsin deficiency (PiMZ) who also have COPD or emphysema. Researchers will use CT scans and blood tests over three years to track how lung density changes. The goal is to find better ways to measure disease progression in this group, which could help design future treatment studies.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Columbia University Irving Medical Center

    NOT_YET_RECRUITING

    New York, New York, 10032, United States

    Contact

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • National Jewish Health

    NOT_YET_RECRUITING

    Denver, Colorado, 80206, United States

    Contact Email: •••••@•••••

    Contact

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35233, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of California- Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Chicago

    NOT_YET_RECRUITING

    Chicago, Illinois, 60637, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.