DRY EYE DISEASE

This study tests if a new eye drop, BUFY01, works as well as an existing one, SVS20, for treating dry eye disease. About 80 adults with dry eyes will use one of the two drops daily for three months. Researchers will check eye health and symptoms to see if both treatments provide …

This study tests whether a new eye drop (BUFY02) works as well as an existing one (TRB02) for treating dry eye disease. About 80 people with dry eye for at least 3 months will use the drops daily for 3 months. Researchers will check eye health and symptoms to see if both treatmen…

This study tests a new combination eye drop (lifitegrast plus perfluorohexyloctane) for people with dry eye disease. About 423 adults will use the drops twice a day for 4 weeks. The goal is to see if the combo improves eye surface damage and symptoms better than existing treatmen…

This study tests a new artificial tear formula (ABBV-444) against a standard brand (Refresh Optive) in 250 adults with dry eye disease. Participants use the assigned eye drops for 90 days, and researchers track symptom relief using a questionnaire and eye exams. The goal is to se…

This study tests an experimental eye drop called GRF312 5% in 100 adults with dry eye disease. The goal is to see if it is safe and helps relieve symptoms. Participants will use the eye drops at home and attend regular check-ups.

This study is testing two new artificial tear formulas to see if they are safe for people with moderate dry eye disease. About 148 adults who already use artificial tears will take part. Researchers will watch for side effects and check eye health during the study.

This study tests whether an eye ointment called Vit-A-Vision can relieve symptoms of dry eye disease, such as burning, irritation, and tired eyes. About 77 adults with dry eye will use the ointment for 30 days. Researchers will measure tear film stability and symptom scores to se…

This study looks at eye changes in cancer patients who have dry eye disease after a stem cell transplant (graft-versus-host disease). Researchers will collect eye samples from 150 adults to find new treatment targets and markers. The goal is to better understand why this eye dama…

This study looks at whether the amount of iron in tears is linked to how severe dry eye disease is. Researchers will compare tear samples from 52 people with dry eyes and healthy eyes. The goal is to find a new way to diagnose and understand dry eye better.