Diabetic neuropathies

This study tested whether custom silicone toe orthoses (inserts) could reduce foot pressure and prevent pre-ulcerative lesions in people with diabetic neuropathy. Sixty participants with diabetes and foot deformities wore the orthoses for six months. The goal was to see if these …

Diabetic polyneuropathy damages nerves in the feet, dulling the sense of touch and raising the risk of unnoticed injuries. This trial tests whether transcutaneous electrical nerve stimulation (TENS) can restore that sensation. Researchers compare high-frequency TENS, low-frequenc…

This trial tests whether electrical stimulation—using TENS and NMES—can improve nerve function and physical activity in people with diabetic peripheral neuropathy. Sixty adults aged 55–65 with type 2 diabetes and neuropathy will receive either real or placebo stimulation sessions…

This study tested a non-invasive ear-clip device that gently stimulates the vagus nerve to see if it can reduce pain in people with diabetic peripheral neuropathy. 185 adults with type 2 diabetes and chronic nerve pain used the device or a sham version twice daily for 12 weeks. T…

This small pilot study tested whether a 4-week course of repetitive transcranial magnetic stimulation (rTMS) can reduce nerve pain and improve quality of life in 18 adults with diabetic neuropathy. Participants received rTMS and were monitored using questionnaires, nerve tests, a…

This study tested whether foot-ankle exercises and walking exercises can reduce foot nerve pain, stress, and improve quality of life in people with type 2 diabetes. 375 adults with diabetes were split into three groups: foot-ankle exercises, walking exercises, or standard care. T…

This study looked at how different shoe fit guidelines affect pressure inside the shoe for people with diabetes and nerve damage. Researchers measured foot pressure while 26 participants walked in standardized shoes with different toe gap sizes. The goal was to see which fit guid…