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Ear stimulation device shows promise for diabetic nerve pain

NCT ID NCT06292962

First seen Jun 10, 2026 · Last updated Jun 22, 2026 · Updated 2 times

Summary

This study tested a non-invasive ear-clip device that gently stimulates the vagus nerve to see if it can reduce pain in people with diabetic peripheral neuropathy. 185 adults with type 2 diabetes and chronic nerve pain used the device or a sham version twice daily for 12 weeks. The trial measured changes in pain levels, inflammation, and nerve health to determine if this drug-free approach could offer relief.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Shifa Hospital

    Lahore, Pakistan

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

non-invasive transcutaneous vagal nerve stimulation (tVNS) device

What this could lead to

If it works, this could provide a safe, drug-free way to ease chronic nerve pain in people with diabetes, potentially reducing reliance on pain medications.

What could go wrong

This is a completed trial, but results are not yet published. The effect may be small or no better than a sham device, and benefits may not apply to everyone with diabetic neuropathy.

Conditions

The condition(s) this trial relates to.

diabetes mellitus diabetic neuropathy neuralgia Pain type 2 diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.