DIABETE TYPE 2

This large phase 3 trial is testing whether colchicine (a gout medication) and low-dose aspirin, taken together or alone, can prevent heart attacks, strokes, and cardiac death in 10,000 high-risk people with type 2 diabetes who have not yet had a heart-related event. Participants…

This study tests a new magnetic device that creates a connection between two parts of the small intestine, aiming to improve blood sugar control in type 2 diabetes. Only 5 adults with diabetes and a BMI between 25 and 50 will be enrolled. The main goal is to see if the device can…

This study tests whether giving a healthy food voucher to people with type 2 diabetes or prediabetes who have low income can improve their blood sugar control. About 390 participants will be randomly assigned to receive the voucher or not. The main goal is to see if hemoglobin A1…

This study looks at whether empagliflozin, a medicine used for diabetes, can help blood vessels and heart muscle recover after a heart attack. About 80 people who had a severe heart attack will either receive empagliflozin or standard care. Researchers will measure artery stiffne…

This study tests whether a new combination drug works better than taking two separate medicines for people with both high blood pressure and type 2 diabetes. About 228 adults will take either the combo pill or a single-ingredient pill for 12 weeks. Researchers will check changes …

This study looks at whether a diode laser, apple cider vinegar, or a plant extract called gymnema sylvestre can kill bacteria in root canals better than standard treatments. It involves 90 adults with type 2 diabetes who have a tooth infection called apical periodontitis. Partici…

This study is testing a gel that turns into a gel when warmed, used alongside standard gum disease treatment. It includes 70 adults, some with type 2 diabetes and some without, to see if the gel helps gums heal better and if healing differs between the two groups. Participants wi…

This study looks at whether taking a daily supplement made from artichoke by-products, combined with a calorie-controlled Mediterranean diet, can help prevent type 2 diabetes in people who are overweight or obese. Researchers will measure changes in insulin resistance and weight …

This study aims to better understand how blood flow and sugar use in the brain are altered in Alzheimer's disease, especially in people who also have type 2 diabetes. Researchers will use advanced PET scans to measure these changes in 60 participants across three groups: people w…

This study is looking for 500 adults with Parkinson's disease, Alzheimer's disease, or type 2 diabetes to help researchers find new ways to diagnose and monitor these conditions. The goal is to identify markers in the blood and brain scans that could lead to earlier detection and…

This study aims to identify subgroups of people with diabetes who share similar patterns between their blood sugar levels and mental health. By using smartphone surveys and continuous glucose monitors, researchers will create 'digital twins'—virtual models that can predict how me…

This study looks at why people with type 2 diabetes often develop heart problems. Researchers will collect blood and urine from 90 volunteers—some with diabetes and heart disease, some with diabetes only, and some healthy—to study special cells called endothelial progenitor cells…

This study is looking for 120 adults with type 2 diabetes to help researchers understand why some people develop high pressure on their feet while walking. High foot pressure can lead to painful ulcers. The goal is to find simple measurements that can predict this risk and create…

This study looks at how long people with type 2 diabetes need to stop taking GLP-1 medications (like semaglutide) before surgery to make sure their stomach is empty. These drugs slow down digestion, which can increase the risk of food or liquid entering the lungs during anesthesi…