Dexamethasone

Researchers are testing whether an intravenous dose of the steroid dexamethasone makes spinal anesthesia last longer in adults having lower abdominal or orthopedic surgery. Participants receive either 8 mg of dexamethasone in saline or a plain saline placebo before their spinal i…

After surgery to remove a benign parotid tumor, some people develop salivary fistulas or sialoceles, which are collections of saliva that can leak or cause swelling. This pilot study tests whether injecting a long-acting local anesthetic called bupivacaine, combined with a steroi…

This study tests two ways to numb the arm for wrist fracture surgery in people at high risk for severe pain. One method uses a long-acting numbing drug (liposomal bupivacaine) plus regular bupivacaine, and the other uses a steroid (dexamethasone) plus regular bupivacaine. The goa…

This trial tests whether olanzapine can replace dexamethasone in preventing delayed nausea and vomiting after chemotherapy in breast cancer patients who have metabolic risk factors like diabetes or obesity. Participants receive either an olanzapine-based regimen or the standard d…

This study will test whether giving dexamethasone, dexmedetomidine, or both right after gallbladder surgery helps the gut start working again sooner. 160 adults having laparoscopic gallbladder removal will be randomly assigned to one of four groups, including a placebo. The main …

This study compares two different doses of the steroid dexamethasone (0.3 mg/kg vs. 0.6 mg/kg) given by mouth to children aged 4-15 who come to the emergency department with an asthma attack. The goal is to see which dose works better at reducing the need for another steroid pres…

This study looks at how giving dexamethasone (a steroid) with a nerve block affects the amount of the numbing drug bupivacaine in the blood. Forty patients having shoulder surgery will receive the nerve block, with dexamethasone given either near the nerve or into a vein. Researc…