DESMOPLASTIC SMALL ROUND CELL TUMOR
Clinical trials for DESMOPLASTIC SMALL ROUND CELL TUMOR explained in plain language.
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New drug combo targets rare childhood cancer
Disease control Recruiting nowThis study tests two chemotherapy drugs, lurbinectedin and irinotecan, in 20 patients aged 15 and older with advanced DSRCT that cannot be surgically removed. The goal is to shrink or control the tumor and track side effects. An optional genetic analysis will help researchers und…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE2 • Sponsor: Italian Sarcoma Group • Aim: Disease control
Last updated May 26, 2026 05:39 UTC
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New stem cell approach aims to boost immune attack on tough childhood cancers
Disease control Recruiting nowThis study tests a stem cell transplant that removes certain immune cells (alpha/beta T cells and CD19+ B cells) and adds a drug called zoledronic acid to help the donor cells fight solid tumors that have come back or not responded to treatment. It includes children and young adu…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: University of Florida • Aim: Disease control
Last updated May 26, 2026 04:38 UTC
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New hope for young sarcoma patients: experimental drug combo enters trials
Disease control Recruiting nowThis study tests a new drug called PEEL-224 combined with two standard chemotherapy drugs (vincristine and temozolomide) in adolescents and young adults whose sarcomas have returned or not responded to prior treatment. The goal is to find the safest dose and see if the combinatio…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: David S Shulman, MD • Aim: Disease control
Last updated May 22, 2026 13:51 UTC
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Engineered immune cells take on childhood cancers in new trial
Disease control Recruiting nowThis early-stage trial tests a personalized cell therapy for children and young adults (up to age 21) with solid tumors that have come back or not responded to standard treatment. Doctors take the patient's own immune cells, modify them to recognize a protein called B7-H3 on tumo…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1 • Sponsor: St. Jude Children's Research Hospital • Aim: Disease control
Last updated May 19, 2026 11:59 UTC
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New hope for rare sarcomas: immune drug plus chemo tested
Disease control Recruiting nowThis study tests whether adding the immunotherapy drug tislelizumab to standard chemotherapy can help shrink or control advanced soft tissue sarcomas that cannot be removed by surgery. About 45 adults aged 18-75 with certain sarcoma types will receive the combination as their fir…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE2 • Sponsor: Fudan University • Aim: Disease control
Last updated May 13, 2026 16:03 UTC
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New hope for rare childhood cancers: drug trial targets stubborn sarcomas
Disease control Recruiting nowThis study is testing a drug called lurbinectedin in people aged 10 and older whose solid tumors (like Ewing sarcoma) have come back or not responded to standard treatment. The goal is to see if the drug is safe and can shrink tumors or delay their growth. Participants must have …
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: PHASE1, PHASE2 • Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated May 11, 2026 20:40 UTC
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New registry aims to unlock secrets of rare childhood cancer
Knowledge-focused Recruiting nowThis study creates a database of health information from up to 250 people with desmoplastic small round cell tumor (DSRCT), a rare cancer. Participants of any age can join by sharing their medical history and ongoing health data. The goal is to help researchers learn more about D…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Sponsor: Memorial Sloan Kettering Cancer Center • Aim: Knowledge-focused
Last updated May 26, 2026 05:37 UTC
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500 rare sarcoma patients enrolled to unlock immune secrets
Knowledge-focused Recruiting nowThis study aims to learn more about the immune system's role in rare types of sarcoma, a group of cancers. Researchers will collect medical information and tissue samples from 500 patients with these rare sarcomas. The goal is to find patterns that could lead to better treatments…
Matched conditions: DESMOPLASTIC SMALL ROUND CELL TUMOR
Phase: NA • Sponsor: Institut Claudius Regaud • Aim: Knowledge-focused
Last updated May 18, 2026 12:03 UTC