CYSTIC FIBROSIS
Clinical trials for CYSTIC FIBROSIS explained in plain language.
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Cystic fibrosis drug repurposed: can a liver medication fix lung function?
Disease control TerminatedThis early-phase trial tested whether glycerol phenylbutyrate (Ravicti), a drug already used for urea cycle disorders, could help restore chloride transport in the nasal cells of adults with cystic fibrosis. The study enrolled 16 participants and compared low-dose Ravicti to a pl…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: National Jewish Health • Aim: Disease control
Last updated Jun 22, 2026 11:55 UTC
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Cystic fibrosis drug trial halted early – what we know
Disease control TerminatedThis study tested a drug called (R)-Roscovitine in adults with cystic fibrosis who also have a chronic lung infection with Pseudomonas aeruginosa. The goal was to see if increasing doses of the drug were safe. The study was terminated early, so results are limited.
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE2 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Jun 16, 2026 12:48 UTC
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Gene therapy inhaler for cystic fibrosis tested, but study stopped early
Disease control TerminatedThis study tested a single dose of an inhaled gene therapy called BI 3720931 in adults with cystic fibrosis who cannot use standard CFTR modulator drugs. The goal was to see if it was safe and could improve lung function. The study was stopped early after enrolling only 5 people,…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Jun 08, 2026 13:07 UTC
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Growth hormone trial for cystic fibrosis wasting falls short
Symptom relief TerminatedThis early-phase study tested whether growth hormone could help adults with cystic fibrosis who were underweight gain weight and muscle. Only 5 people took part before the study was stopped early. The goal was to see if the hormone could improve appetite, body weight, and quality…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1 • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated Jun 22, 2026 12:06 UTC
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AI stethoscope could spot lung disease patterns
Knowledge-focused TerminatedThis study tested whether artificial intelligence can detect and classify abnormal lung sounds in people with cystic fibrosis, COPD, or pulmonary fibrosis. Researchers recorded lung sounds with an electronic stethoscope during routine checkups and analyzed them using AI. The goal…
Matched conditions: CYSTIC FIBROSIS
Sponsor: Groupe Hospitalier de la Region de Mulhouse et Sud Alsace • Aim: Knowledge-focused
Last updated Jun 23, 2026 11:55 UTC
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Cystic fibrosis study aims to build a research database, not test a cure
Knowledge-focused TerminatedThis study is for people with cystic fibrosis and their family members. Its goal is to collect medical information and biological samples during regular clinic visits. These will be stored and used by researchers to learn more about how cystic fibrosis affects the body and how it…
Matched conditions: CYSTIC FIBROSIS
Sponsor: National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) • Aim: Knowledge-focused
Last updated Jun 22, 2026 11:58 UTC
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Cystic fibrosis study investigates hidden lung infections
Knowledge-focused TerminatedThis study aimed to find out how common non-tuberculous mycobacteria (NTM) infections are in people with cystic fibrosis in France. Researchers collected sputum samples and blood from 848 patients to compare culture tests with a newer serology (antibody) test. The goal was to bet…
Matched conditions: CYSTIC FIBROSIS
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:09 UTC
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CF gene repair study halted early: lab tests show promise but trial ends
Knowledge-focused TerminatedThis study aimed to see if a special molecule (oligonucleotide blocker) could fix the genetic glitch in cells from people with cystic fibrosis. Researchers planned to test this on cells from 16 patients aged 12 and older. The trial was terminated early, so results are limited to …
Matched conditions: CYSTIC FIBROSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:07 UTC