CROHN'S DISEASE (CD)

This study tests a new drug called BCD-261 in adults with moderate to severe active Crohn's disease who have not responded well to previous treatments. About 204 participants will receive either BCD-261 or a placebo to see if the drug can reduce symptoms and improve bowel inflamm…

This study tests a medicine called vedolizumab in children and teenagers with moderate to severe Crohn's disease. The goal is to see if the drug can keep symptoms under control and reduce gut inflammation over a year. Participants first receive three infusions over six weeks, the…

This study looks at whether replacing normal food with special milkshakes for 6 weeks can help biologic drugs work better for children aged 6-18 with active Crohn's disease. Crohn's is a long-term gut condition that needs ongoing management. The goal is to see if this diet reduce…

This study tests whether a ketogenic (low-carb, high-fat) or carnivore (meat-only) diet can improve quality of life and reduce symptoms in 160 adults with inflammatory bowel disease (Crohn's or ulcerative colitis) or rheumatoid arthritis. Participants are randomly assigned to one…

This pilot study is testing how well ibuprofen and acetaminophen work for period cramps in women with Crohn's disease. The goal is to see if a larger study is possible by tracking enrollment, adherence, and completion. Participants will take each medication for two menstrual cycl…

This study follows 200 adults with Crohn's disease or ulcerative colitis who are prescribed Zymfentra as part of their normal care. Participants answer online surveys about their bowel symptoms over one year. The goal is to see if Zymfentra helps reduce symptoms and improve disea…