CRITICAL CARE

This study tests a new method for adjusting ventilator support in ICU patients with acute breathing failure. Instead of the usual approach based on breath size and rate, doctors will use a target based on the patient's own breathing effort. The goal is to see if this leads to mor…

This study tests a new, non-invasive treatment for septic shock, a life-threatening condition where the body's response to infection causes dangerous inflammation. The treatment uses focused ultrasound waves to stimulate the spleen, which may help reduce levels of inflammatory ch…

This study tests a program called EMPOWER to help family members who make medical decisions for critically ill patients. It compares EMPOWER to supportive conversations to see if it reduces symptoms of grief, PTSD, and depression. About 172 participants will be followed for up to…

This study watches how hospitals around the world help patients get stronger after being on a breathing machine in the ICU. It will include about 2,400 adults and track what rehab they get, how it affects their recovery, and their quality of life after leaving the hospital. The g…

This study looks at how well two different software programs measure heart function in people with septic shock, a life-threatening infection. Researchers will compare measurements from 60 adult patients to see if the software gives consistent results. The goal is to improve how …

This study looks at the medical records of 7,000 adults who spent at least 5 days in the intensive care unit (ICU). The goal is to find patterns among those who stay for more than 10-14 days, a condition called Persistent Critical Illness. By grouping patients based on their heal…

This study looks at why some patients become very weak after being in the intensive care unit (ICU). Researchers will take blood and small muscle samples from 20 high-risk surgical patients to find chemical markers linked to this weakness. The goal is to better understand the pro…