COLITIS, ULCERATIVE

This study tested an experimental drug called TEV-48574 in 290 adults with moderate to severe ulcerative colitis or Crohn's disease. The goal was to see if the drug could help patients achieve remission or reduce bowel inflammation after 14 weeks of treatment. Participants receiv…

This study tested a drug called ustekinumab in 112 children with moderate-to-severe ulcerative colitis, a chronic bowel disease. The goal was to see if the drug could reduce symptoms like diarrhea and bleeding and help the colon heal. Children first received the drug through an I…

This study looked at 688 people in South Korea with ulcerative colitis or Crohn's disease who were treated with Kynteles (vedolizumab) as part of their regular care. The main goal was to track side effects and see how many patients felt better after treatment. The results help do…

This study tested an experimental drug called MORF-057 in 39 adults with moderate-to-severe ulcerative colitis, a chronic inflammatory bowel disease. The goal was to see if the drug could reduce gut inflammation and improve symptoms over 12 weeks. Participants took the drug by mo…

This study tested two doses of an oral medication, ozanimod, in 198 Japanese adults with moderate to severe ulcerative colitis. The goal was to see if the drug could reduce symptoms like diarrhea and rectal bleeding compared to a placebo. The trial is now complete, and results wi…

This study tested an experimental drug called JNJ-77242113 in 252 adults with moderate to severe ulcerative colitis. The goal was to see if the drug could reduce symptoms like diarrhea and rectal bleeding better than a placebo. Participants took the drug or a placebo for 12 weeks…

This study tested an experimental drug called BI 655130 in 22 adults with mild-to-moderate ulcerative colitis who were already taking a TNF inhibitor. The goal was to see if adding BI 655130 could help heal the lining of the colon and improve symptoms. The trial focused on safety…

This study tested a drug called vedolizumab in 121 children with moderate to severe ulcerative colitis, a condition causing inflammation and pain in the gut. The goal was to see if the drug could bring about remission—meaning symptoms improve and the gut looks nearly normal on a …

This study looked at the long-term safety of a drug called spesolimab in 79 adults with moderate to severe ulcerative colitis who had already taken part in earlier studies. The main goal was to track side effects over time, and researchers also checked how many patients achieved …

This study tested a drug called spesolimab in 98 adults with moderate-to-severe ulcerative colitis who did not get better with previous biologic treatments. The goal was to see if the drug could reduce symptoms and inflammation, aiming for remission. The trial was completed and u…

This study looked at physical fitness in 100 children and teens (ages 10-17) with chronic inflammatory bowel disease (Crohn's disease, ulcerative colitis, or unclassified colitis) and compared them to healthy kids of the same age, weight, and sex. Researchers measured cardiorespi…

This early study tested a new drug called BI 655130 in 8 adults with moderate to severe ulcerative colitis. The main goal was to see how the drug affects genes in the gut lining, not to prove it works as a treatment. Researchers also checked safety and inflammation markers. Becau…

This study observed 92 adults with Crohn's disease or ulcerative colitis who were already taking or starting vedolizumab. Researchers watched whether patients chose intravenous infusions at a clinic or injections at home, and how long they stayed on their chosen treatment. The go…