COAGULOPATHY

This study looked at whether giving whole blood (blood with all parts intact) works as well as giving separate blood components (red cells, plasma, platelets) to trauma patients with severe bleeding and clotting problems. About 200 patients took part. The goal was to see if whole…

This study tested whether a special donor plasma product (OctaplasLG) can help treat blood clotting problems in people with septic shock. The trial included 60 adults with septic shock and clotting issues. Researchers measured how quickly treatment was given and looked at surviva…

This study tested a freeze-dried plasma that can be mixed and used in just 6 minutes, without needing a blood type match. It included 42 trauma patients with severe bleeding. The goal was to see if this quick-to-use plasma helps control bleeding better than standard frozen plasma…

This study looked at 30 adults with sepsis to understand how changes in tiny blood vessels under the tongue relate to blood clotting problems. Researchers measured blood vessel health, oxygen levels, and clotting factors. The goal was to learn more about these connections, not to…

This early-stage study tested the safety of a new spray-dried plasma product called FrontlineODP in 24 healthy adults. Participants received one, two, or four units of the product, and their safety was compared to those receiving standard frozen plasma. The goal was to see if the…