New Quick-Acting powder could save lives in severe trauma bleeding
NCT ID NCT05449834
First seen Jan 23, 2026 · Last updated May 20, 2026 · Updated 16 times
Summary
This study tests whether a fast-acting powder form of fibrinogen (a protein that helps blood clot) works better than the standard frozen blood product for severe trauma patients with major bleeding. About 850 adults from Australia and New Zealand who need blood transfusions and have low fibrinogen levels will be randomly assigned to receive either the powder or standard care. The main goal is to see how many days patients are alive and out of the hospital 90 days after injury.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Phone: •••-•••-•••• Email: •••••@•••••
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Alfred Hospital
RECRUITINGMelbourne, Victoria, 3004, Australia
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Aukland City Hospital
NOT_YET_RECRUITINGAuckland, Aukland, 1023, New Zealand
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Cairns Hospital
RECRUITINGCairns, Queensland, 4870, Australia
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Flinders Medical Centre
RECRUITINGAdelaide, South Australia, 5042, Australia
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Gold Coast University Hospital
RECRUITINGGold Coast, Queensland, 4215, Australia
Contact
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John Hunter Hospital
RECRUITINGNewcastle, New South Wales, 2305, Australia
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Liverpool Hospital
RECRUITINGSydney, New South Wales, 2170, Australia
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Middlemore Hospital
NOT_YET_RECRUITINGAuckland, Aukland, 2025, New Zealand
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Princess Alexandra Hospital
RECRUITINGBrisbane, Queensland, 4102, Australia
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Rockhampton Hospital
RECRUITINGRockhampton, Queensland, 4700, Australia
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Royal Adelaide Hospital
RECRUITINGAdelaide, South Australia, 5000, Australia
Contact
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Royal Brisbane and Women's Hospital
RECRUITINGBrisbane, Queensland, 4006, Australia
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Royal Darwin Hospital
RECRUITINGDarwin, Northern Territory, 0810, Australia
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Royal Hobart Hospital
RECRUITINGHobart, Tasmania, 7000, Australia
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Royal Melbourne Hospital
RECRUITINGMelbourne, Victoria, 3050, Australia
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Royal North Shore Hospital
RECRUITINGSydney, New South Wales, 2065, Australia
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Royal Perth Hospital
RECRUITINGPerth, Western Australia, 6000, Australia
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Royal Prince Alfred Hospital
RECRUITINGSydney, New South Wales, 2050, Australia
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St Vincent's Hospital
RECRUITINGSydney, New South Wales, 2010, Australia
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Sunshine Coast University Hospital
RECRUITINGSunshine Coast, Queensland, 4575, Australia
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Townsville Hospital
RECRUITINGTownsville, Queensland, 4814, Australia
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Waikato Hospital
RECRUITINGHamilton, Hamilton, 3204, New Zealand
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Wellington Hospital
RECRUITINGWellington, Wellington Region, 6021, New Zealand
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Westmead Hospital
RECRUITINGSydney, New South Wales, 2145, Australia
Conditions
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