CLOSTRIDIOIDES DIFFICILE INFECTION
Clinical trials for CLOSTRIDIOIDES DIFFICILE INFECTION explained in plain language.
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New drug combo shows promise against deadly gut infection
Disease control CompletedThis study tested whether adding the drug bezlotoxumab to standard treatment could prevent serious outcomes like organ failure, infection return, or death in people with a severe C. diff infection. The trial included 44 adults who were identified as high-risk using a special scor…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Hellenic Institute for the Study of Sepsis • Aim: Disease control
Last updated May 26, 2026 08:42 UTC
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Gut bacteria capsules take on superbugs in hospital patients
Disease control CompletedThis study tested whether taking capsules containing healthy gut bacteria could help clear drug-resistant germs (including C. difficile) from the intestines of 42 hospitalized adults on long-term antibiotics. The main goal was to see if the germs disappeared from stool after 14 d…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE1, PHASE2 • Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran • Aim: Disease control
Last updated May 26, 2026 08:34 UTC
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New c. diff drug shows promise in early trial
Disease control CompletedThis study tested a new drug called CRS3123 against the standard treatment vancomycin for C. diff infection, a serious gut infection. 43 adults with a first or second infection took either CRS3123 or vancomycin. The goal was to see if CRS3123 is safe and can cure the infection as…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Crestone, Inc • Aim: Disease control
Last updated May 18, 2026 12:04 UTC
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New drug AZD5148 tested in healthy volunteers – no treatment yet
Knowledge-focused CompletedThis early-stage study tested a single dose of AZD5148 in 16 healthy Japanese adults to see if it is safe and how the body processes it. Participants received the drug either as an injection into a vein or muscle, or a placebo. The goal was only to gather safety and drug-level in…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated May 20, 2026 11:55 UTC