CLOSTRIDIOIDES DIFFICILE INFECTION
Clinical trials for CLOSTRIDIOIDES DIFFICILE INFECTION explained in plain language.
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New drug challenge to standard c. diff treatment
Disease control CompletedThis study compared a new investigational antibiotic, CRS3123, to the standard antibiotic vancomycin for treating adults with a first or second episode of C. difficile infection (CDI). It involved 43 participants and aimed to see if the new drug was safe and could stop diarrhea a…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Crestone, Inc • Aim: Disease control
Last updated Apr 03, 2026 23:35 UTC
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Friendly bacteria capsules battle hospital superbugs
Disease control CompletedThis study tested whether giving capsules containing healthy gut bacteria from donors could help clear dangerous, drug-resistant germs from hospitalized patients who need long-term antibiotics. Forty-two patients received either the bacteria capsules or identical placebo pills. R…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE1, PHASE2 • Sponsor: Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Trial aims to stop deadly gut infection in High-Risk patients
Disease control CompletedThis study tested if adding the drug bezlotoxumab to standard care could prevent severe outcomes in patients with a dangerous C. difficile gut infection. It focused on 44 patients identified as high-risk using a special score based on their genes, blood tests, and gut bacteria. T…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE2 • Sponsor: Hellenic Institute for the Study of Sepsis • Aim: Disease control
Last updated Mar 23, 2026 15:15 UTC
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First human test for new gut infection drug
Knowledge-focused CompletedThis early-stage study aimed to check the safety and see how the body processes a single dose of a new drug called AZD5148. It involved 16 healthy Japanese adults who received the drug either as a shot in the muscle or through an IV. The main goal was to monitor for any side effe…
Matched conditions: CLOSTRIDIOIDES DIFFICILE INFECTION
Phase: PHASE1 • Sponsor: AstraZeneca • Aim: Knowledge-focused
Last updated Apr 03, 2026 14:43 UTC